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The gradient between wedged and free hepatic venous pressures was measured in patients with alcoholic cirrhosis before and 1, 3, and 9 months after continuous oral administration of propranolol at doses reducing the heart rate by 25% or after administration of a placebo. The gradient between wedged and free hepatic venous pressures decreased throughout the duration of propranolol administration, and it did not significantly change in the patients receiving placebo. Since the gradient between wedged and free hepatic venous pressures closely reflects portal venous pressure in alcoholic cirrhosis, it is concluded that continuous oral administration of propranolol produced sustained reduction in portal venous pressure in these patients.
D Lebrec, and
P Hillon, and
C Muńoz, and
G Goldfarb, and
O Nouel, and
J P Benhamou
December 1986,
Digestive diseases and sciences,
D Lebrec, and
P Hillon, and
C Muńoz, and
G Goldfarb, and
O Nouel, and
J P Benhamou
January 2002,
Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology,
D Lebrec, and
P Hillon, and
C Muńoz, and
G Goldfarb, and
O Nouel, and
J P Benhamou
January 1986,
Hepatology (Baltimore, Md.),
D Lebrec, and
P Hillon, and
C Muńoz, and
G Goldfarb, and
O Nouel, and
J P Benhamou
December 2007,
Gut and liver,
D Lebrec, and
P Hillon, and
C Muńoz, and
G Goldfarb, and
O Nouel, and
J P Benhamou
September 1987,
Clinical pharmacology and therapeutics,
D Lebrec, and
P Hillon, and
C Muńoz, and
G Goldfarb, and
O Nouel, and
J P Benhamou
January 2015,
Patient preference and adherence,
D Lebrec, and
P Hillon, and
C Muńoz, and
G Goldfarb, and
O Nouel, and
J P Benhamou
April 1986,
Chirurgia italiana,
D Lebrec, and
P Hillon, and
C Muńoz, and
G Goldfarb, and
O Nouel, and
J P Benhamou
August 2009,
Journal of hepatology,
D Lebrec, and
P Hillon, and
C Muńoz, and
G Goldfarb, and
O Nouel, and
J P Benhamou
January 1985,
Gut,
D Lebrec, and
P Hillon, and
C Muńoz, and
G Goldfarb, and
O Nouel, and
J P Benhamou
June 1989,
British journal of clinical pharmacology,
