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Experiments were conducted on the dog internal carotid artery (with circulatory isolation); the following peculiarities of the effects of the prostaglandins (PG) under study were revealed: PG-E1 caused either a constrictory or a dilatory effect, and PG-E1--a constrictory effect only; in the former case the artery became accustomed with repetition of the action, and in the latter case it did not become accustomed. The duration of the PG-E2 effects, particularly of relaxation, was much greater than of the serotonin effects; residual contraction of the vascular smooth muscles was frequent; PG-E1 and PG-E2 intensified the effects of serotonin, and, partially, of noradrenaline.
G I Mchedlishvili, and
L G Ormotsadze
January 1980,
Advances in prostaglandin and thromboxane research,
G I Mchedlishvili, and
L G Ormotsadze
February 1979,
Prostaglandins,
G I Mchedlishvili, and
L G Ormotsadze
April 1982,
Biulleten' eksperimental'noi biologii i meditsiny,
G I Mchedlishvili, and
L G Ormotsadze
October 1974,
Nature,
G I Mchedlishvili, and
L G Ormotsadze
February 1976,
Biomedical mass spectrometry,
G I Mchedlishvili, and
L G Ormotsadze
July 1974,
Surgical neurology,
G I Mchedlishvili, and
L G Ormotsadze
January 1977,
Farmakologiia i toksikologiia,
G I Mchedlishvili, and
L G Ormotsadze
April 1968,
Life sciences,
G I Mchedlishvili, and
L G Ormotsadze
January 1992,
Prostaglandins,
G I Mchedlishvili, and
L G Ormotsadze
December 1976,
Prostaglandins,
