Biomaterial Database

The effect of intranasal beclomethasone dipropionate on the recurrence of nasal polyps after ethmoidectomy. 1980

E Virolainen, and H Puhakka

The purpose of this work was to examine in a double blind study the ability of beclomethasone dipropionate to prevent recurrence of nasal polyps in patients in whom radical ethmoidectomy had been performed immediately before. It analyzes the results in terms of the patients subjective symptoms, clinical status and rhinomanometry. After the follow-up period of one year 86% of the patients in the beclomethasone group and 60% in the placebo group had no subjective nasal symptoms. In clinical examination polyps were absent in 54% in the beclomethasone group and in 13% in the placebo group. Rhinomanometrically there was normal nasal patency in 68% in the beclomethasone and in 33% in the placebo group.

UI	MeSH Term	Description	Entries
D008297	Male		Males
D008365	Manometry	Measurement of the pressure or tension of liquids or gases with a manometer.	Tonometry,Manometries
D008875	Middle Aged	An adult aged 45 - 64 years.	Middle Age
D009298	Nasal Polyps	Focal accumulations of EDEMA fluid in the NASAL MUCOSA accompanied by HYPERPLASIA of the associated submucosal connective tissue. Polyps may be NEOPLASMS, foci of INFLAMMATION, degenerative lesions, or malformations.	Nasal Polyp,Polyp, Nasal,Polyps, Nasal
D010919	Placebos	Any dummy medication or treatment. Although placebos originally were medicinal preparations having no specific pharmacological activity against a targeted condition, the concept has been extended to include treatments or procedures, especially those administered to control groups in clinical trials in order to provide baseline measurements for the experimental protocol.	Sham Treatment
D012008	Recurrence	The return of a sign, symptom, or disease after a remission.	Recrudescence,Relapse,Recrudescences,Recurrences,Relapses
D002986	Clinical Trials as Topic	Works about pre-planned studies of the safety, efficacy, or optimum dosage schedule (if appropriate) of one or more diagnostic, therapeutic, or prophylactic drugs, devices, or techniques selected according to predetermined criteria of eligibility and observed for predefined evidence of favorable and unfavorable effects. This concept includes clinical trials conducted both in the U.S. and in other countries.	Clinical Trial as Topic
D004311	Double-Blind Method	A method of studying a drug or procedure in which both the subjects and investigators are kept unaware of who is actually getting which specific treatment.	Double-Masked Study,Double-Blind Study,Double-Masked Method,Double Blind Method,Double Blind Study,Double Masked Method,Double Masked Study,Double-Blind Methods,Double-Blind Studies,Double-Masked Methods,Double-Masked Studies,Method, Double-Blind,Method, Double-Masked,Methods, Double-Blind,Methods, Double-Masked,Studies, Double-Blind,Studies, Double-Masked,Study, Double-Blind,Study, Double-Masked
D005005	Ethmoid Sinus	The numerous (6-12) small thin-walled spaces or air cells in the ETHMOID BONE located between the eyes. These air cells form an ethmoidal labyrinth.	Bulla Ethmoidalis,Ethmoid Bulla,Ethmoid Sinuses,Ethmoidal Air Cells,Haller Cell,Infraorbital Ethmoid Cell,Onodi Air Cell,Sphenoethmoidal Air Cell,Air Cell, Ethmoidal,Air Cell, Onodi,Bulla Ethmoidali,Bulla, Ethmoid,Cell, Ethmoidal Air,Cell, Haller,Cell, Infraorbital Ethmoid,Cell, Sphenoethmoidal Air,Ethmoid Cell, Infraorbital,Ethmoid Sinuse,Ethmoidal Air Cell,Infraorbital Ethmoid Cells,Sinus, Ethmoid,Sphenoethmoidal Air Cells
D005260	Female		Females