Tolciclate versus miconazole, a double-blind trial in patients with dermatomycosis. 1980

L C Cucè, and B F Assunção, and L G Medawar, and A Salibian, and W Groppi

Eighty-one patients with dermatomycosis such as tinea corporis, tinea cruris, tinea pedis and pityriasis versicolor were treated with tolciclate 1% cream or miconazole 2% cream. Parasitological cure was obtained in 100% of the patients given tolciclate and in 97.4% of those given miconazole. Patients and investigator considered tolciclate treatment as excellent, respectively, in 76.2% and 73.8% of the cases. The corresponding figures for miconazole were 74.4% and 66.7%. Both treatments were well tolerated.

UI MeSH Term Description Entries
D007093 Imidazoles Compounds containing 1,3-diazole, a five membered aromatic ring containing two nitrogen atoms separated by one of the carbons. Chemically reduced ones include IMIDAZOLINES and IMIDAZOLIDINES. Distinguish from 1,2-diazole (PYRAZOLES).
D008297 Male Males
D008825 Miconazole An imidazole antifungal agent that is used topically and by intravenous infusion. Brentan,Dactarin,Miconasil Nitrate,Miconazole Nitrate,Monistat,R-14,889,Nitrate, Miconasil,Nitrate, Miconazole,R 14,889,R14,889
D010043 Outcome and Process Assessment, Health Care Evaluation procedures that focus on both the outcome or status (OUTCOMES ASSESSMENT) of the patient at the end of an episode of care - presence of symptoms, level of activity, and mortality; and the process (ASSESSMENT, PROCESS) - what is done for the patient diagnostically and therapeutically. Outcome and Process Assessment (Health Care),Donabedian Model,Donabedian Triad,Outcome and Process Assessment,Structure Process Outcome Triad,Model, Donabedian,Triad, Donabedian
D010915 Pityriasis A name originally applied to a group of skin diseases characterized by the formation of fine, branny scales, but now used only with a modifier. (Dorland, 27th ed) Pityriases
D002986 Clinical Trials as Topic Works about pre-planned studies of the safety, efficacy, or optimum dosage schedule (if appropriate) of one or more diagnostic, therapeutic, or prophylactic drugs, devices, or techniques selected according to predetermined criteria of eligibility and observed for predefined evidence of favorable and unfavorable effects. This concept includes clinical trials conducted both in the U.S. and in other countries. Clinical Trial as Topic
D003881 Dermatomycoses Superficial infections of the skin or its appendages by any of various fungi. Skin Diseases, Fungal,Dermatomycosis,Dermatophyte Infection,Fungal Skin Diseases
D004311 Double-Blind Method A method of studying a drug or procedure in which both the subjects and investigators are kept unaware of who is actually getting which specific treatment. Double-Masked Study,Double-Blind Study,Double-Masked Method,Double Blind Method,Double Blind Study,Double Masked Method,Double Masked Study,Double-Blind Methods,Double-Blind Studies,Double-Masked Methods,Double-Masked Studies,Method, Double-Blind,Method, Double-Masked,Methods, Double-Blind,Methods, Double-Masked,Studies, Double-Blind,Studies, Double-Masked,Study, Double-Blind,Study, Double-Masked
D005260 Female Females
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man

Related Publications

L C Cucè, and B F Assunção, and L G Medawar, and A Salibian, and W Groppi
January 1973, Acta dermato-venereologica,
L C Cucè, and B F Assunção, and L G Medawar, and A Salibian, and W Groppi
January 1988, Dermatologica,
L C Cucè, and B F Assunção, and L G Medawar, and A Salibian, and W Groppi
January 1982, The Journal of international medical research,
L C Cucè, and B F Assunção, and L G Medawar, and A Salibian, and W Groppi
February 1995, International journal of dermatology,
L C Cucè, and B F Assunção, and L G Medawar, and A Salibian, and W Groppi
January 1984, Medicina cutanea ibero-latino-americana,
L C Cucè, and B F Assunção, and L G Medawar, and A Salibian, and W Groppi
January 1979, Indian journal of dermatology, venereology and leprology,
L C Cucè, and B F Assunção, and L G Medawar, and A Salibian, and W Groppi
October 1987, Mykosen,
L C Cucè, and B F Assunção, and L G Medawar, and A Salibian, and W Groppi
May 1975, Mykosen,
L C Cucè, and B F Assunção, and L G Medawar, and A Salibian, and W Groppi
September 1989, Clinical and experimental dermatology,
L C Cucè, and B F Assunção, and L G Medawar, and A Salibian, and W Groppi
July 1976, Current therapeutic research, clinical and experimental,
Copied contents to your clipboard!