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Miscroscopic changes in the liver tissue of mice became detectable 42 hours after the administration of gricine through the appearance of porphyrins in the plasma of hepatocytes marked by the enlargement of their volume, nuclei, and nucleoli. 72 hours after gricine, porphyrins were also found in the lumina of capilary bile ducts and hepatic ducts. This was accompanied by dispersion extinction of hepatocytes and pigment accumulation in the plasma of Kupffer's cells. There was histochemically proved increased activity of alkaline and acidic phosphatase, G6PDH, NADH and NADPH tetrazolium reductase. Under electron microscopy, the porphyrins showed crystalline structure, rotated the plane of polarized light, and were marked by red fluorescence.
A Chlumská, and
J Dobiás, and
V Janousek
January 2009,
Patologicheskaia fiziologiia i eksperimental'naia terapiia,
A Chlumská, and
J Dobiás, and
V Janousek
May 1965,
Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.),
A Chlumská, and
J Dobiás, and
V Janousek
January 1945,
Biulleten' eksperimental'noi biologii i meditsiny,
A Chlumská, and
J Dobiás, and
V Janousek
January 1963,
Biochimica et biophysica acta,
A Chlumská, and
J Dobiás, and
V Janousek
January 1952,
Minerva medicolegale; archivio di antropologia criminale, psichiatria, e medicina legale,
A Chlumská, and
J Dobiás, and
V Janousek
January 1969,
Revista espanola de las enfermedades del aparato digestivo,
A Chlumská, and
J Dobiás, and
V Janousek
January 1978,
Indian journal of pathology & microbiology,
A Chlumská, and
J Dobiás, and
V Janousek
January 1975,
Zhurnal eksperimental'noi i klinicheskoi meditsiny,
A Chlumská, and
J Dobiás, and
V Janousek
January 2001,
Vestnik khirurgii imeni I. I. Grekova,
A Chlumská, and
J Dobiás, and
V Janousek
February 1966,
The Biochemical journal,
