BIOMAT Database Logo BIOMAT Database Logo

The effect of levamisole on human chromosomes. 1980

R Berger, and A Bernheim, and J Feingold, and J M Andrieu

The effects of levamisole on human chromosomes have been studied using lymphocyte cultures. A slight excess of chromatid and chromosome breaks and gaps was observed in both in vitro and in vivo studies. An excess of SCE was observed in vivo but not in vitro when similar levamisole concentrations were used.

UI MeSH Term Description Entries
D007978 Levamisole An antihelminthic drug that has been tried experimentally in rheumatic disorders where it apparently restores the immune response by increasing macrophage chemotaxis and T-lymphocyte function. Paradoxically, this immune enhancement appears to be beneficial in rheumatoid arthritis where dermatitis, leukopenia, and thrombocytopenia, and nausea and vomiting have been reported as side effects. (From Smith and Reynard, Textbook of Pharmacology, 1991, p435-6) L-Tetramisole,Levotetramisole,Decaris,Dekaris,Levamisole Hydrochloride,Solaskil,Hydrochloride, Levamisole
D002842 Chromatids Either of the two longitudinally adjacent threads formed when a eukaryotic chromosome replicates prior to mitosis. The chromatids are held together at the centromere. Sister chromatids are derived from the same chromosome. (Singleton & Sainsbury, Dictionary of Microbiology and Molecular Biology, 2d ed) Chromatid
D002869 Chromosome Aberrations Abnormal number or structure of chromosomes. Chromosome aberrations may result in CHROMOSOME DISORDERS. Autosome Abnormalities,Cytogenetic Aberrations,Abnormalities, Autosome,Abnormalities, Chromosomal,Abnormalities, Chromosome,Chromosomal Aberrations,Chromosome Abnormalities,Cytogenetic Abnormalities,Aberration, Chromosomal,Aberration, Chromosome,Aberration, Cytogenetic,Aberrations, Chromosomal,Aberrations, Chromosome,Aberrations, Cytogenetic,Abnormalities, Cytogenetic,Abnormality, Autosome,Abnormality, Chromosomal,Abnormality, Chromosome,Abnormality, Cytogenetic,Autosome Abnormality,Chromosomal Aberration,Chromosomal Abnormalities,Chromosomal Abnormality,Chromosome Aberration,Chromosome Abnormality,Cytogenetic Aberration,Cytogenetic Abnormality
D003434 Crossing Over, Genetic The reciprocal exchange of segments at corresponding positions along pairs of homologous CHROMOSOMES by symmetrical breakage and crosswise rejoining forming cross-over sites (HOLLIDAY JUNCTIONS) that are resolved during CHROMOSOME SEGREGATION. Crossing-over typically occurs during MEIOSIS but it may also occur in the absence of meiosis, for example, with bacterial chromosomes, organelle chromosomes, or somatic cell nuclear chromosomes. Crossing Over,Crossing-Over, Genetic,Crossing Overs,Genetic Crossing Over,Genetic Crossing-Over
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D012854 Sister Chromatid Exchange An exchange of segments between the sister chromatids of a chromosome, either between the sister chromatids of a meiotic tetrad or between the sister chromatids of a duplicated somatic chromosome. Its frequency is increased by ultraviolet and ionizing radiation and other mutagenic agents and is particularly high in BLOOM SYNDROME. Chromatid Exchange, Sister,Chromatid Exchanges, Sister,Exchange, Sister Chromatid,Exchanges, Sister Chromatid,Sister Chromatid Exchanges
D066298 In Vitro Techniques Methods to study reactions or processes taking place in an artificial environment outside the living organism. In Vitro Test,In Vitro Testing,In Vitro Tests,In Vitro as Topic,In Vitro,In Vitro Technique,In Vitro Testings,Technique, In Vitro,Techniques, In Vitro,Test, In Vitro,Testing, In Vitro,Testings, In Vitro,Tests, In Vitro,Vitro Testing, In

Related Publications

R Berger, and A Bernheim, and J Feingold, and J M Andrieu
Effect of levamisole on the human monocyte IgG receptor.
March 1977, Journal of immunology (Baltimore, Md. : 1950),
R Berger, and A Bernheim, and J Feingold, and J M Andrieu
Effect of levamisole on human granulopoiesis in vitro.
November 1977, Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.),
R Berger, and A Bernheim, and J Feingold, and J M Andrieu
The effect of pyrimethamine on the human chromosomes.
July 1965, Revista brasileira de biologia,
R Berger, and A Bernheim, and J Feingold, and J M Andrieu
[On the effect of cytostatic agents on human chromosomes].
April 1968, Internationale Zeitschrift fur klinische Pharmakologie, Therapie, und Toxikologie. International journal of clinical pharmacology, therapy, and toxicology,
R Berger, and A Bernheim, and J Feingold, and J M Andrieu
Diphenylhydantoin: effect on the chromosomes of human leukocytes.
March 1971, American journal of obstetrics and gynecology,
R Berger, and A Bernheim, and J Feingold, and J M Andrieu
THE EFFECT OF 5-BROMODEOXYURIDINE ON HUMAN CHROMOSOMES.
March 1964, Experimental cell research,
R Berger, and A Bernheim, and J Feingold, and J M Andrieu
The effect of tritiated thymidine on human chromosomes.
January 1971, In vitro,
R Berger, and A Bernheim, and J Feingold, and J M Andrieu
[The effect of ionising radiations on human chromosomes].
April 1969, Archivio per le scienze mediche,
R Berger, and A Bernheim, and J Feingold, and J M Andrieu
The effect of levamisole on human lymphocyte mediator production in vitro.
February 1976, Cellular immunology,
R Berger, and A Bernheim, and J Feingold, and J M Andrieu
Effect of chlordiazepoxide hydrochloride on human chromosomes.
March 1970, American journal of obstetrics and gynecology,
Copied contents to your clipboard!