Biomaterial Database

Rapid assessment of cardiac output and central blood volumes from indicator dilution curves without precalculation using programmable calculators. 1980

M A Cole, and D W Crawford

The program described here provides complete analysis of the indicator dilution curve by incorporating densitometric calibration and logarithmic downslope fit for the widely used Hewlett-Packard 67/97 hand calculator series. Densitometric sensitivity is calculated from the linear regression as the dye calibration factor; thus, direct entry of the dye curve deflections eliminate the necessity to precalculate curve concentration. The program displays appropriate sequential time intervals prompting deflection entry of the upslope and initial exponential downslope of the curve. The remainder of the curve is generated from the logarithmically extrapolated initial downslope, and the area of the curve is then obtained for calculation of cardiac output, mean transit time, and central blood volume. Programming versatility and the rapid (4--5 min) immediate analysis of indicator dilution curves are thus available.

UI	MeSH Term	Description	Entries
D007201	Indicator Dilution Techniques	Methods for assessing flow through a system by injection of a known quantity of an indicator, such as a dye, radionuclide, or chilled liquid, into the system and monitoring its concentration over time at a specific point in the system. (From Dorland, 28th ed)	Dilution Techniques,Dilution Technics,Indicator Dilution Technics,Dilution Technic,Dilution Technic, Indicator,Dilution Technics, Indicator,Dilution Technique,Dilution Technique, Indicator,Dilution Techniques, Indicator,Indicator Dilution Technic,Indicator Dilution Technique,Technic, Dilution,Technic, Indicator Dilution,Technics, Dilution,Technics, Indicator Dilution,Technique, Dilution,Technique, Indicator Dilution,Techniques, Dilution,Techniques, Indicator Dilution
D009862	Online Systems	Computer-based Information systems having real-time remote access to information or processes.	On-Line Systems,On Line Systems,On-Line System,Online System,System, On-Line,System, Online,Systems, On-Line,Systems, Online
D001810	Blood Volume	Volume of circulating BLOOD. It is the sum of the PLASMA VOLUME and ERYTHROCYTE VOLUME.	Blood Volumes,Volume, Blood,Volumes, Blood
D001811	Blood Volume Determination	Method for determining the circulating blood volume by introducing a known quantity of foreign substance into the blood and determining its concentration some minutes later when thorough mixing has occurred. From these two values the blood volume can be calculated by dividing the quantity of injected material by its concentration in the blood at the time of uniform mixing. Generally expressed as cubic centimeters or liters per kilogram of body weight.	Blood Volume Determinations,Determination, Blood Volume,Determinations, Blood Volume,Volume Determination, Blood,Volume Determinations, Blood
D002302	Cardiac Output	The volume of BLOOD passing through the HEART per unit of time. It is usually expressed as liters (volume) per minute so as not to be confused with STROKE VOLUME (volume per beat).	Cardiac Outputs,Output, Cardiac,Outputs, Cardiac
D003201	Computers	Programmable electronic devices designed to accept data, perform prescribed mathematical and logical operations at high speed, and display the results of these operations.	Calculators, Programmable,Computer Hardware,Computers, Digital,Hardware, Computer,Calculator, Programmable,Computer,Computer, Digital,Digital Computer,Digital Computers,Programmable Calculator,Programmable Calculators
D003720	Densitometry	The measurement of the density of a material by measuring the amount of light or radiation passing through (or absorbed by) the material.	Densitometries
D006801	Humans	Members of the species Homo sapiens.	Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man