BIOMAT Database Logo BIOMAT Database Logo

Prostaglandins in renovascular and renal hypertension. 1978

A Hornych, and F Fontaliran, and M Safar, and T T Guyene, and J Bariety, and P Milliez

PG A1, B1, E2, F1,2alpha and PRA have been measured in 8 hypertensive patients with unilateral renal arterial stenosis, 7 hypertensive patients with unilateral renal atrophy and 20 control normotensive subjects. PRA and PGA1 were significantly increased in patients with renovascular hypertension but not in patients with atrophy. PGE2 and PGF1,2alpha were increased in both groups of patients, especially on the stenotic or atrophic side. The increase of PGA1 and PGE2, represents a secondary antihypertensive, diuretic and natriuretic mechanism, the increase of PGF1,2alpha a direct hypertensive mechanism.

UI MeSH Term Description Entries
D006977 Hypertension, Renal Persistent high BLOOD PRESSURE due to KIDNEY DISEASES, such as those involving the renal parenchyma, the renal vasculature, or tumors that secrete RENIN. Hypertensions, Renal,Renal Hypertension,Renal Hypertensions
D006978 Hypertension, Renovascular Hypertension due to RENAL ARTERY OBSTRUCTION or compression. Hypertension, Goldblatt,Goldblatt Syndrome,Goldblatt Hypertension,Renovascular Hypertension,Syndrome, Goldblatt
D008875 Middle Aged An adult aged 45 - 64 years. Middle Age
D011453 Prostaglandins A group of compounds derived from unsaturated 20-carbon fatty acids, primarily arachidonic acid, via the cyclooxygenase pathway. They are extremely potent mediators of a diverse group of physiological processes. Prostaglandin,Prostanoid,Prostanoids
D011454 Prostaglandins A (13E,15S)-15-Hydroxy-9-oxoprosta-10,13-dien-1-oic acid (PGA(1)); (5Z,13E,15S)-15-hydroxy-9-oxoprosta-5,10,13-trien-1-oic acid (PGA(2)); (5Z,13E,15S,17Z)-15-hydroxy-9-oxoprosta-5,10,13,17-tetraen-1-oic acid (PGA(3)). A group of naturally occurring secondary prostaglandins derived from PGE; PGA(1) and PGA(2) as well as their 19-hydroxy derivatives are found in many organs and tissues. PGA
D011456 Prostaglandins B Physiologically active prostaglandins found in many tissues and organs. They are potent pressor substances and have many other physiological activities. PGB
D011458 Prostaglandins E (11 alpha,13E,15S)-11,15-Dihydroxy-9-oxoprost-13-en-1-oic acid (PGE(1)); (5Z,11 alpha,13E,15S)-11,15-dihydroxy-9-oxoprosta-5,13-dien-1-oic acid (PGE(2)); and (5Z,11 alpha,13E,15S,17Z)-11,15-dihydroxy-9-oxoprosta-5,13,17-trien-1-oic acid (PGE(3)). Three of the six naturally occurring prostaglandins. They are considered primary in that no one is derived from another in living organisms. Originally isolated from sheep seminal fluid and vesicles, they are found in many organs and tissues and play a major role in mediating various physiological activities. PGE
D011460 Prostaglandins F (9 alpha,11 alpha,13E,15S)-9,11,15-Trihydroxyprost-13-en-1-oic acid (PGF(1 alpha)); (5Z,9 alpha,11,alpha,13E,15S)-9,11,15-trihydroxyprosta-5,13-dien-1-oic acid (PGF(2 alpha)); (5Z,9 alpha,11 alpha,13E,15S,17Z)-9,11,15-trihydroxyprosta-5,13,17-trien-1-oic acid (PGF(3 alpha)). A family of prostaglandins that includes three of the six naturally occurring prostaglandins. All naturally occurring PGF have an alpha configuration at the 9-carbon position. They stimulate uterine and bronchial smooth muscle and are often used as oxytocics. PGF
D012083 Renin A highly specific (Leu-Leu) endopeptidase that generates ANGIOTENSIN I from its precursor ANGIOTENSINOGEN, leading to a cascade of reactions which elevate BLOOD PRESSURE and increase sodium retention by the kidney in the RENIN-ANGIOTENSIN SYSTEM. The enzyme was formerly listed as EC 3.4.99.19. Angiotensin-Forming Enzyme,Angiotensinogenase,Big Renin,Cryorenin,Inactive Renin,Pre-Prorenin,Preprorenin,Prorenin,Angiotensin Forming Enzyme,Pre Prorenin,Renin, Big,Renin, Inactive
D001794 Blood Pressure PRESSURE of the BLOOD on the ARTERIES and other BLOOD VESSELS. Systolic Pressure,Diastolic Pressure,Pulse Pressure,Pressure, Blood,Pressure, Diastolic,Pressure, Pulse,Pressure, Systolic,Pressures, Systolic

Related Publications

A Hornych, and F Fontaliran, and M Safar, and T T Guyene, and J Bariety, and P Milliez
Letter: Renovascular hypertension and renal prostaglandins.
June 1976, Archives of internal medicine,
A Hornych, and F Fontaliran, and M Safar, and T T Guyene, and J Bariety, and P Milliez
Renal vascular interaction of angiotensin II and prostaglandins in renovascular hypertension.
July 1999, Journal of cardiovascular pharmacology,
A Hornych, and F Fontaliran, and M Safar, and T T Guyene, and J Bariety, and P Milliez
Renal vein prostaglandins in renovascular hypertensive patients.
September 1985, Prostaglandins, leukotrienes, and medicine,
A Hornych, and F Fontaliran, and M Safar, and T T Guyene, and J Bariety, and P Milliez
[Renal hypertension (renal parenchymal and renovascular hypertension, etc.)].
January 1996, Ryoikibetsu shokogun shirizu,
A Hornych, and F Fontaliran, and M Safar, and T T Guyene, and J Bariety, and P Milliez
Renal function in renal and renovascular hypertension.
September 1966, Postgraduate medicine,
A Hornych, and F Fontaliran, and M Safar, and T T Guyene, and J Bariety, and P Milliez
Renal Transplantation and Renovascular Hypertension.
July 2022, The Journal of urology,
A Hornych, and F Fontaliran, and M Safar, and T T Guyene, and J Bariety, and P Milliez
Renal Transplantation and Renovascular Hypertension.
April 2023, The Journal of urology,
A Hornych, and F Fontaliran, and M Safar, and T T Guyene, and J Bariety, and P Milliez
Renal transplantation and renovascular hypertension.
November 2010, The Journal of urology,
A Hornych, and F Fontaliran, and M Safar, and T T Guyene, and J Bariety, and P Milliez
Renal Transplantation and Renovascular Hypertension.
December 2022, The Journal of urology,
A Hornych, and F Fontaliran, and M Safar, and T T Guyene, and J Bariety, and P Milliez
Renal Transplantation and Renovascular Hypertension.
October 2021, The Journal of urology,
Copied contents to your clipboard!