Biomaterial Database

Ulcerative lichen planus. Follow-up of surgical excision and grafting. 1980

C P Crotty, and W P Su, and R K Winkelmann

Four patients with ulcerative lichen planus of the feet underwent total excision and split-thickness skin grafting of the affected areas. One patient underwent grafting in 1951, and remained free of recurrent ulcers for 26 years. Another, who had an 18-year follow-up after grafting, required an additional procedure. The possibility of squamous cell carcinoma in ulcerative lichen planus is considerable, lending further support to the concept that excision with grafting is the treatment of choice for these lesions.

UI	MeSH Term	Description	Entries
D008010	Lichen Planus	An inflammatory, pruritic disease of the skin and mucous membranes, which can be either generalized or localized. It is characterized by distinctive purplish, flat-topped papules having a predilection for the trunk and flexor surfaces. The lesions may be discrete or coalesce to form plaques. Histologically, there is a "saw-tooth" pattern of epidermal hyperplasia and vacuolar alteration of the basal layer of the epidermis along with an intense upper dermal inflammatory infiltrate composed predominantly of T-cells. Etiology is unknown.	Cutaneous Lichen Planus,Lichen Planopilaris,Lichen Ruber Planus,Mucosal Lichen Planus,Lichen Rubra Planus,Lichen Planus, Cutaneous,Lichen Planus, Mucosal,Planopilaris, Lichen
D008297	Male		Males
D008875	Middle Aged	An adult aged 45 - 64 years.	Middle Age
D005260	Female		Females
D005500	Follow-Up Studies	Studies in which individuals or populations are followed to assess the outcome of exposures, procedures, or effects of a characteristic, e.g., occurrence of disease.	Followup Studies,Follow Up Studies,Follow-Up Study,Followup Study,Studies, Follow-Up,Studies, Followup,Study, Follow-Up,Study, Followup
D005528	Foot	The distal extremity of the leg in vertebrates, consisting of the tarsus (ANKLE); METATARSUS; phalanges; and the soft tissues surrounding these bones.	Feet
D006801	Humans	Members of the species Homo sapiens.	Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000328	Adult	A person having attained full growth or maturity. Adults are of 19 through 44 years of age. For a person between 19 and 24 years of age, YOUNG ADULT is available.	Adults
D000368	Aged	A person 65 years of age or older. For a person older than 79 years, AGED, 80 AND OVER is available.	Elderly
D012883	Skin Ulcer	An ULCER of the skin and underlying tissues.	Skin Ulcers,Ulcer, Skin,Ulcers, Skin