BIOMAT Database Logo BIOMAT Database Logo

[Transplacental passage of the antiviral agent, bonafton]. 1980

V P Kurnaeva, and V A Proĭnova, and V L Ponomareva, and N L Aĭzina, and E V Shmeleva

The ability of 14C-bonafton to penetrate the placental bar was studied in female Wistar rats. The drug was shown to penetrate through the placenta in insignificant amounts. The maximal quantities of the drug which entered the fetuses proper during the last third of pregnancy do not exceed 0.55% of 14C-bonafton content in the mother's blood. It was revealed that bonafton transplacental penetration is barred by fetal envelopes.

UI MeSH Term Description Entries
D008431 Maternal-Fetal Exchange Exchange of substances between the maternal blood and the fetal blood at the PLACENTA via PLACENTAL CIRCULATION. The placental barrier excludes microbial or viral transmission. Transplacental Exposure,Exchange, Maternal-Fetal,Exposure, Transplacental,Maternal Fetal Exchange
D009285 Naphthoquinones Naphthalene rings which contain two ketone moieties in any position. They can be substituted in any position except at the ketone groups. Naphthalenediones,Naphthazarins,Naphthoquinone
D010920 Placenta A highly vascularized mammalian fetal-maternal organ and major site of transport of oxygen, nutrients, and fetal waste products. It includes a fetal portion (CHORIONIC VILLI) derived from TROPHOBLASTS and a maternal portion (DECIDUA) derived from the uterine ENDOMETRIUM. The placenta produces an array of steroid, protein and peptide hormones (PLACENTAL HORMONES). Placentoma, Normal,Placentome,Placentas,Placentomes
D011247 Pregnancy The status during which female mammals carry their developing young (EMBRYOS or FETUSES) in utero before birth, beginning from FERTILIZATION to BIRTH. Gestation,Pregnancies
D002250 Carbon Radioisotopes Unstable isotopes of carbon that decay or disintegrate emitting radiation. C atoms with atomic weights 10, 11, and 14-16 are radioactive carbon isotopes. Radioisotopes, Carbon
D005260 Female Females
D005321 Extraembryonic Membranes The thin layers of tissue that surround the developing embryo. There are four extra-embryonic membranes commonly found in VERTEBRATES, such as REPTILES; BIRDS; and MAMMALS. They are the YOLK SAC, the ALLANTOIS, the AMNION, and the CHORION. These membranes provide protection and means to transport nutrients and wastes. Fetal Membranes,Extra-Embryonic Membranes,Extra Embryonic Membranes,Extra-Embryonic Membrane,Extraembryonic Membrane,Fetal Membrane,Membrane, Extra-Embryonic,Membrane, Extraembryonic,Membrane, Fetal,Membranes, Extra-Embryonic,Membranes, Extraembryonic,Membranes, Fetal
D005333 Fetus The unborn young of a viviparous mammal, in the postembryonic period, after the major structures have been outlined. In humans, the unborn young from the end of the eighth week after CONCEPTION until BIRTH, as distinguished from the earlier EMBRYO, MAMMALIAN. Fetal Structures,Fetal Tissue,Fetuses,Mummified Fetus,Retained Fetus,Fetal Structure,Fetal Tissues,Fetus, Mummified,Fetus, Retained,Structure, Fetal,Structures, Fetal,Tissue, Fetal,Tissues, Fetal
D005865 Gestational Age The age of the conceptus, beginning from the time of FERTILIZATION. In clinical obstetrics, the gestational age is often estimated from the onset of the last MENSTRUATION which is about 2 weeks before OVULATION and fertilization. It is also estimated to begin from fertilization, estrus, coitus, or artificial insemination. Embryologic Age,Fetal Maturity, Chronologic,Chronologic Fetal Maturity,Fetal Age,Maturity, Chronologic Fetal,Age, Embryologic,Age, Fetal,Age, Gestational,Ages, Embryologic,Ages, Fetal,Ages, Gestational,Embryologic Ages,Fetal Ages,Gestational Ages
D000653 Amniotic Fluid A clear, yellowish liquid that envelopes the FETUS inside the sac of AMNION. In the first trimester, it is likely a transudate of maternal or fetal plasma. In the second trimester, amniotic fluid derives primarily from fetal lung and kidney. Cells or substances in this fluid can be removed for prenatal diagnostic tests (AMNIOCENTESIS). Amniotic Fluid Index,Amniotic Fluid Indices,Amniotic Fluids,Fluid Index, Amniotic,Fluid Indices, Amniotic,Fluid, Amniotic,Fluids, Amniotic,Index, Amniotic Fluid,Indices, Amniotic Fluid

Related Publications

V P Kurnaeva, and V A Proĭnova, and V L Ponomareva, and N L Aĭzina, and E V Shmeleva
Transplacental passage of a nonionic contrast agent.
July 2005, European journal of pediatrics,
V P Kurnaeva, and V A Proĭnova, and V L Ponomareva, and N L Aĭzina, and E V Shmeleva
Comment to "Transplacental passage of a nonionic contrast agent".
September 2006, European journal of pediatrics,
V P Kurnaeva, and V A Proĭnova, and V L Ponomareva, and N L Aĭzina, and E V Shmeleva
Transplacental passage of the non-ionic contrast agent iopamidol in twins.
April 2011, Pediatric radiology,
V P Kurnaeva, and V A Proĭnova, and V L Ponomareva, and N L Aĭzina, and E V Shmeleva
Another case of transplacental passage of the non-ionic contrast agent ioversol.
July 2007, Pediatric radiology,
V P Kurnaeva, and V A Proĭnova, and V L Ponomareva, and N L Aĭzina, and E V Shmeleva
[Transplacental passage of doxorubicin].
January 1989, Journal de gynecologie, obstetrique et biologie de la reproduction,
V P Kurnaeva, and V A Proĭnova, and V L Ponomareva, and N L Aĭzina, and E V Shmeleva
[Transplacental passage of triiodothyronine].
January 1959, Bulletin de la Federation des societes de gynecologie et dobstetrique de langue francaise,
V P Kurnaeva, and V A Proĭnova, and V L Ponomareva, and N L Aĭzina, and E V Shmeleva
Transplacental passage of insulin.
January 1991, The New England journal of medicine,
V P Kurnaeva, and V A Proĭnova, and V L Ponomareva, and N L Aĭzina, and E V Shmeleva
Transplacental passage of ampicillin.
January 1966, British medical journal,
V P Kurnaeva, and V A Proĭnova, and V L Ponomareva, and N L Aĭzina, and E V Shmeleva
Transplacental passage of erythrocytes.
January 1968, Bibliotheca haematologica,
V P Kurnaeva, and V A Proĭnova, and V L Ponomareva, and N L Aĭzina, and E V Shmeleva
Transplacental passage of pesticides.
May 1970, American journal of obstetrics and gynecology,
Copied contents to your clipboard!