Virulence of Escherichia coli in acute pyelonephritis, acute cystitis and asymptomatic bacteriuria. 1980

J F van den Bosch, and P L Oe, and P Postma, and J de Graaff, and D M MacLaren, and W H Jansen, and P A Guinée

E. coli strains were isolated from urine specimens of hospitalised patients with acute pyelonephritis, acute cystitis or asymptomatic bacteriuria (ABU), and tested for virulence in an experimental mouse model. Of 12 pyelonephritis-strains 11 were shown to be virulent and 1 avirulent; of 12 cystitis-strains 4 were virulent and 8 avirulent; of 12 ABU-strains 5 were virulent and 7 avirulent. It is concluded that, while no difference in virulence was found between cystitis- and ABU-strains, pyelonephritis-strains were more often virulent than cystitis- and ABU-strains. No associations could be shown between virulence of the isolated strains and the presence of antibody-coated bacteria in the urine. Common urinary O types were not more often virulent than other O types. No relationship was seen between virulence and the presence of K antigen or the presence of particular K types.

UI MeSH Term Description Entries
D011704 Pyelonephritis Inflammation of the KIDNEY involving the renal parenchyma (the NEPHRONS); KIDNEY PELVIS; and KIDNEY CALICES. It is characterized by ABDOMINAL PAIN; FEVER; NAUSEA; VOMITING; and occasionally DIARRHEA. Necrotizing Pyelonephritis,Pyelonephritis, Acute Necrotizing,Pyelonephritides
D003556 Cystitis Inflammation of the URINARY BLADDER, either from bacterial or non-bacterial causes. Cystitis is usually associated with painful urination (dysuria), increased frequency, urgency, and suprapubic pain. Cystitides
D004926 Escherichia coli A species of gram-negative, facultatively anaerobic, rod-shaped bacteria (GRAM-NEGATIVE FACULTATIVELY ANAEROBIC RODS) commonly found in the lower part of the intestine of warm-blooded animals. It is usually nonpathogenic, but some strains are known to produce DIARRHEA and pyogenic infections. Pathogenic strains (virotypes) are classified by their specific pathogenic mechanisms such as toxins (ENTEROTOXIGENIC ESCHERICHIA COLI), etc. Alkalescens-Dispar Group,Bacillus coli,Bacterium coli,Bacterium coli commune,Diffusely Adherent Escherichia coli,E coli,EAggEC,Enteroaggregative Escherichia coli,Enterococcus coli,Diffusely Adherent E. coli,Enteroaggregative E. coli,Enteroinvasive E. coli,Enteroinvasive Escherichia coli
D004927 Escherichia coli Infections Infections with bacteria of the species ESCHERICHIA COLI. E coli Infections,E. coli Infection,Infections, E coli,Infections, Escherichia coli,E coli Infection,E. coli Infections,Escherichia coli Infection,Infection, E coli,Infection, E. coli,Infection, Escherichia coli
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000208 Acute Disease Disease having a short and relatively severe course. Acute Diseases,Disease, Acute,Diseases, Acute
D000818 Animals Unicellular or multicellular, heterotrophic organisms, that have sensation and the power of voluntary movement. Under the older five kingdom paradigm, Animalia was one of the kingdoms. Under the modern three domain model, Animalia represents one of the many groups in the domain EUKARYOTA. Animal,Metazoa,Animalia
D001437 Bacteriuria The presence of bacteria in the urine which is normally bacteria-free. These bacteria are from the URINARY TRACT and are not contaminants of the surrounding tissues. Bacteriuria can be symptomatic or asymptomatic. Significant bacteriuria is an indicator of urinary tract infection. Bacteriurias
D012703 Serotyping Process of determining and distinguishing species of bacteria or viruses based on antigens they share. Serotypings
D014556 Urine Liquid by-product of excretion produced in the kidneys, temporarily stored in the bladder until discharge through the URETHRA.

Related Publications

J F van den Bosch, and P L Oe, and P Postma, and J de Graaff, and D M MacLaren, and W H Jansen, and P A Guinée
December 2016, Journal of clinical and diagnostic research : JCDR,
J F van den Bosch, and P L Oe, and P Postma, and J de Graaff, and D M MacLaren, and W H Jansen, and P A Guinée
April 1996, European journal of epidemiology,
J F van den Bosch, and P L Oe, and P Postma, and J de Graaff, and D M MacLaren, and W H Jansen, and P A Guinée
January 2009, International journal of medical microbiology : IJMM,
J F van den Bosch, and P L Oe, and P Postma, and J de Graaff, and D M MacLaren, and W H Jansen, and P A Guinée
June 1984, Postgraduate medicine,
J F van den Bosch, and P L Oe, and P Postma, and J de Graaff, and D M MacLaren, and W H Jansen, and P A Guinée
August 2003, Infection,
J F van den Bosch, and P L Oe, and P Postma, and J de Graaff, and D M MacLaren, and W H Jansen, and P A Guinée
January 1981, Infection and immunity,
J F van den Bosch, and P L Oe, and P Postma, and J de Graaff, and D M MacLaren, and W H Jansen, and P A Guinée
November 2011, Journal of clinical microbiology,
J F van den Bosch, and P L Oe, and P Postma, and J de Graaff, and D M MacLaren, and W H Jansen, and P A Guinée
December 2014, International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases,
J F van den Bosch, and P L Oe, and P Postma, and J de Graaff, and D M MacLaren, and W H Jansen, and P A Guinée
April 1968, Das Deutsche Gesundheitswesen,
J F van den Bosch, and P L Oe, and P Postma, and J de Graaff, and D M MacLaren, and W H Jansen, and P A Guinée
May 1975, Acta paediatrica Scandinavica,
Copied contents to your clipboard!