BIOMAT Database Logo BIOMAT Database Logo

Catabolite repression of Escherichia coli heat-stable enterotoxin activity. 1981

M G Martínez-Cadena, and L M Guzman-Verduzco, and H Stieglitz, and Y M Kupersztoch-Portnoy

The Escherichia coli heat-stable enterotoxin (ST) coded for by plasmid pYK007 (Apr ST+) showed a dependence for cyclic adenosine 3',5'-monophosphate (cAMP) to express ST activity in an adenyl cyclase (cya) deletion mutant; no ST activity was detected in the presence of cAMP in a cAMP receptor protein (crp) deletion mutant or in a double deletion mutant (delta cya delta crp). The cya-crp effect on ST activity could not be accounted for by a modification of the copy number of plasmid deoxyribonucleic acid per chromosome equivalent or by an alteration in the secretion of an active intracellular enterotoxin.

UI MeSH Term Description Entries
D009154 Mutation Any detectable and heritable change in the genetic material that causes a change in the GENOTYPE and which is transmitted to daughter cells and to succeeding generations. Mutations
D010957 Plasmids Extrachromosomal, usually CIRCULAR DNA molecules that are self-replicating and transferable from one organism to another. They are found in a variety of bacterial, archaeal, fungal, algal, and plant species. They are used in GENETIC ENGINEERING as CLONING VECTORS. Episomes,Episome,Plasmid
D011953 Receptors, Cyclic AMP Cell surface proteins that bind cyclic AMP with high affinity and trigger intracellular changes which influence the behavior of cells. The best characterized cyclic AMP receptors are those of the slime mold Dictyostelium discoideum. The transcription regulator CYCLIC AMP RECEPTOR PROTEIN of prokaryotes is not included nor are the eukaryotic cytoplasmic cyclic AMP receptor proteins which are the regulatory subunits of CYCLIC AMP-DEPENDENT PROTEIN KINASES. Cyclic AMP Receptors,cAMP Receptors,Cyclic AMP Receptor,Receptors, cAMP,cAMP Receptor,Receptor, Cyclic AMP,Receptor, cAMP
D002872 Chromosome Deletion Actual loss of portion of a chromosome. Monosomy, Partial,Partial Monosomy,Deletion, Chromosome,Deletions, Chromosome,Monosomies, Partial,Partial Monosomies
D004768 Enterotoxins Substances that are toxic to the intestinal tract causing vomiting, diarrhea, etc.; most common enterotoxins are produced by bacteria. Staphylococcal Enterotoxin,Enterotoxin,Staphylococcal Enterotoxins,Enterotoxin, Staphylococcal,Enterotoxins, Staphylococcal
D004926 Escherichia coli A species of gram-negative, facultatively anaerobic, rod-shaped bacteria (GRAM-NEGATIVE FACULTATIVELY ANAEROBIC RODS) commonly found in the lower part of the intestine of warm-blooded animals. It is usually nonpathogenic, but some strains are known to produce DIARRHEA and pyogenic infections. Pathogenic strains (virotypes) are classified by their specific pathogenic mechanisms such as toxins (ENTEROTOXIGENIC ESCHERICHIA COLI), etc. Alkalescens-Dispar Group,Bacillus coli,Bacterium coli,Bacterium coli commune,Diffusely Adherent Escherichia coli,E coli,EAggEC,Enteroaggregative Escherichia coli,Enterococcus coli,Diffusely Adherent E. coli,Enteroaggregative E. coli,Enteroinvasive E. coli,Enteroinvasive Escherichia coli
D005786 Gene Expression Regulation Any of the processes by which nuclear, cytoplasmic, or intercellular factors influence the differential control (induction or repression) of gene action at the level of transcription or translation. Gene Action Regulation,Regulation of Gene Expression,Expression Regulation, Gene,Regulation, Gene Action,Regulation, Gene Expression
D005796 Genes A category of nucleic acid sequences that function as units of heredity and which code for the basic instructions for the development, reproduction, and maintenance of organisms. Cistron,Gene,Genetic Materials,Cistrons,Genetic Material,Material, Genetic,Materials, Genetic
D001427 Bacterial Toxins Toxic substances formed in or elaborated by bacteria; they are usually proteins with high molecular weight and antigenicity; some are used as antibiotics and some to skin test for the presence of or susceptibility to certain diseases. Bacterial Toxin,Toxins, Bacterial,Toxin, Bacterial

Related Publications

M G Martínez-Cadena, and L M Guzman-Verduzco, and H Stieglitz, and Y M Kupersztoch-Portnoy
Repression of heat-stable enterotoxin synthesis in enterotoxigenic Escherichia coli.
September 1977, Infection and immunity,
M G Martínez-Cadena, and L M Guzman-Verduzco, and H Stieglitz, and Y M Kupersztoch-Portnoy
Vascular permeability activity in Escherichia coli heat-stable enterotoxin.
August 1981, Infection and immunity,
M G Martínez-Cadena, and L M Guzman-Verduzco, and H Stieglitz, and Y M Kupersztoch-Portnoy
Production of Escherichia coli STb enterotoxin is subject to catabolite repression.
July 1995, Microbiology (Reading, England),
M G Martínez-Cadena, and L M Guzman-Verduzco, and H Stieglitz, and Y M Kupersztoch-Portnoy
Purification of Escherichia coli heat-stable enterotoxin.
January 1988, Methods in enzymology,
M G Martínez-Cadena, and L M Guzman-Verduzco, and H Stieglitz, and Y M Kupersztoch-Portnoy
Preparative purification of Escherichia coli heat-stable enterotoxin.
December 1985, Analytical biochemistry,
M G Martínez-Cadena, and L M Guzman-Verduzco, and H Stieglitz, and Y M Kupersztoch-Portnoy
Fusion of Escherichia coli heat-stable enterotoxin and heat-labile enterotoxin B subunit.
November 1987, Journal of bacteriology,
M G Martínez-Cadena, and L M Guzman-Verduzco, and H Stieglitz, and Y M Kupersztoch-Portnoy
Heat-stable Escherichia coli enterotoxin production in vivo.
August 1975, Infection and immunity,
M G Martínez-Cadena, and L M Guzman-Verduzco, and H Stieglitz, and Y M Kupersztoch-Portnoy
Monoclonal antibodies to Escherichia coli heat-stable enterotoxin.
June 1984, Lancet (London, England),
M G Martínez-Cadena, and L M Guzman-Verduzco, and H Stieglitz, and Y M Kupersztoch-Portnoy
[Heat-stable enterotoxin produced by enterotoxigenic Escherichia coli].
September 1983, Nihon saikingaku zasshi. Japanese journal of bacteriology,
M G Martínez-Cadena, and L M Guzman-Verduzco, and H Stieglitz, and Y M Kupersztoch-Portnoy
Catabolite repression gene of Escherichia coli.
November 1969, Journal of bacteriology,
Copied contents to your clipboard!