-transparent.png){kind=logo}
The unlabeled antibody peroxidase-antiperoxidase (PAP) method of Sternberger et al. has been employed at the ultramicroscopic level to stain filaments polymerized in vitro from aqueous extracts of multiple sclerosis (MS) plaques. The filaments were heavily decorated with antiserum to the glial fibrillary acidic (GFA) protein but not stained with serum absorbed with GFA protein, preimmunization serum, or anti-rat brain tubulin but was not stained with antiserum to the GFA protein. The present study provides direct morphological evidence that filaments polymerized in vitro from extracts of MS plaques contain the GFA protein.
Related Publications
C V Lucas, and
E P Reaven, and
K G Bensch, and
L F Eng
August 1984,
Brain research,
C V Lucas, and
E P Reaven, and
K G Bensch, and
L F Eng
January 1981,
Progress in clinical and biological research,
C V Lucas, and
E P Reaven, and
K G Bensch, and
L F Eng
September 1982,
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society,
C V Lucas, and
E P Reaven, and
K G Bensch, and
L F Eng
March 1981,
Journal of neuroimmunology,
C V Lucas, and
E P Reaven, and
K G Bensch, and
L F Eng
March 1980,
Neurochemical research,
C V Lucas, and
E P Reaven, and
K G Bensch, and
L F Eng
May 1984,
Brain research,
C V Lucas, and
E P Reaven, and
K G Bensch, and
L F Eng
July 1984,
Nippon Ganka Gakkai zasshi,
C V Lucas, and
E P Reaven, and
K G Bensch, and
L F Eng
July 1983,
Journal of neuropathology and experimental neurology,
C V Lucas, and
E P Reaven, and
K G Bensch, and
L F Eng
January 1985,
Histochemistry,
C V Lucas, and
E P Reaven, and
K G Bensch, and
L F Eng
January 1979,
Acta neurologica Belgica,
