-transparent.png){kind=logo}
The object of this article is to assess the value of human serum albumin (HSA) in the initial resuscitation of hypotensive trauma victims. Thirty-six patients (mean age = 30 years) in shock from trauma who underwent laparotomies were randomly assigned to either Ringer's lactate solution (RL) resuscitation or 4% HSA in RL resuscitation. Both groups received approximately 8L of test fluid and 6U of washed red cells. The only death in the study occurred in a patient assigned to the RL group. Two patients in each group required mechanical ventilation for longer than 24 hours. No differences were noted in a battery of pulmonary function tests performed daily for 5 days. These results demonstrate that HSA is not essential in this clinical setting for safe and effective resuscitation.
G S Moss, and
R J Lowe, and
J Jilek, and
H D Levine
March 2000,
Shock (Augusta, Ga.),
G S Moss, and
R J Lowe, and
J Jilek, and
H D Levine
August 2012,
Resuscitation,
G S Moss, and
R J Lowe, and
J Jilek, and
H D Levine
November 2001,
Shock (Augusta, Ga.),
G S Moss, and
R J Lowe, and
J Jilek, and
H D Levine
November 1984,
Surgery, gynecology & obstetrics,
G S Moss, and
R J Lowe, and
J Jilek, and
H D Levine
January 1984,
Current surgery,
G S Moss, and
R J Lowe, and
J Jilek, and
H D Levine
October 2001,
Intensive & critical care nursing,
G S Moss, and
R J Lowe, and
J Jilek, and
H D Levine
October 1982,
The American surgeon,
G S Moss, and
R J Lowe, and
J Jilek, and
H D Levine
June 2005,
Journal of wound care,
G S Moss, and
R J Lowe, and
J Jilek, and
H D Levine
January 1988,
European surgical research. Europaische chirurgische Forschung. Recherches chirurgicales europeennes,
G S Moss, and
R J Lowe, and
J Jilek, and
H D Levine
January 1997,
Archives of disease in childhood. Fetal and neonatal edition,
