Biomaterial Database

Endothelial cell loss in intraocular lens placement. 1978

R C Drews, and S R Waltman

Endothelial cell counts were done on eyes selected to fall into four categories: unoperated, intracapsular cataract extraction without implantation, and intracapsular cataract extraction with easy or difficult insertion of an intraocular implant. Uncomplicated cataract extraction resulted in less than 9% cell loss. Implantation in "easy" eyes resulted in 12% cell loss (p greater than 0.3). Eyes in which implantation was difficult suffered an average loss of 65% of the endothelial cells (p less than .001). The reasons for cell loss are discussed and some improvements in techniques are mentioned with examples of the value of analysis of motion picture records of the surgery. The obvious lesson to be learned is that everything possible must be done to optimize routinely the conditions for lens implantation. The surgeon who finds conditions unfavorable for lens implantation must consider that persistence will mean sacrificing, on the average, two-thirds of the corneal endothelial cells.

UI	MeSH Term	Description	Entries
D007910	Lenses, Intraocular	Artificial implanted lenses.	Implantable Contact Lens,Lens, Intraocular,Contact Lens, Implantable,Intraocular Lens,Intraocular Lenses,Lens, Implantable Contact
D009040	Motion Pictures	The art, technique, or business of producing motion pictures for entertainment, propaganda, or instruction.	Film,Motion Picture,Movie,Cinema,Films,Films as Topic,Movies,Movies as Topic,Cinemas,Films as Topics,Movies as Topics,Picture, Motion,Pictures, Motion
D002387	Cataract Extraction	The removal of a cataractous CRYSTALLINE LENS from the eye.	Enzymatic Zonulolysis,Phakectomy,Cataract Extractions,Enzymatic Zonulolyses,Extraction, Cataract,Extractions, Cataract,Phakectomies,Zonulolyses, Enzymatic,Zonulolysis, Enzymatic
D002452	Cell Count	The number of CELLS of a specific kind, usually measured per unit volume or area of sample.	Cell Density,Cell Number,Cell Counts,Cell Densities,Cell Numbers,Count, Cell,Counts, Cell,Densities, Cell,Density, Cell,Number, Cell,Numbers, Cell
D003315	Cornea	The transparent anterior portion of the fibrous coat of the eye consisting of five layers: stratified squamous CORNEAL EPITHELIUM; BOWMAN MEMBRANE; CORNEAL STROMA; DESCEMET MEMBRANE; and mesenchymal CORNEAL ENDOTHELIUM. It serves as the first refracting medium of the eye. It is structurally continuous with the SCLERA, avascular, receiving its nourishment by permeation through spaces between the lamellae, and is innervated by the ophthalmic division of the TRIGEMINAL NERVE via the ciliary nerves and those of the surrounding conjunctiva which together form plexuses. (Cline et al., Dictionary of Visual Science, 4th ed)	Corneas
D004727	Endothelium	A layer of epithelium that lines the heart, blood vessels (ENDOTHELIUM, VASCULAR), lymph vessels (ENDOTHELIUM, LYMPHATIC), and the serous cavities of the body.	Endotheliums
D006801	Humans	Members of the species Homo sapiens.	Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D065306	Corneal Injuries	Damage or trauma inflicted to the CORNEA by external means.	Corneal Abrasions,Cornea Injuries,Corneal Damage,Corneal Scar,Corneal Trauma,Abrasion, Corneal,Cornea Injury,Corneal Abrasion,Corneal Damages,Corneal Injury,Corneal Scars,Corneal Traumas,Damage, Corneal,Injury, Cornea,Injury, Corneal,Scar, Corneal,Trauma, Corneal