The uveitis-glaucoma-hyphema syndrome associated with the Mark VIII anterior chamber lens implant. 1978

F T Ellingson

An update on the percentage of my patients showing the UGH syndrome associated with the Mark VIII anterior chamber lens implant as manufactured by Surgidev is given. Of seven patients having the syndrome sufficiently severe to warrant removal of the offending lens, six have now been reimplanted, two each with Rayner, IOLAB, and PC lenses. Whereas, other physicians have observed a similar UGH syndrome associated with iris chafing and erosions, this process was not particularly apparent in my cases involving the Surgidev lens. As for the chafing phenomenon, one could logically assume that it could be in large part eliminated by significantly increasing the curvature of the lens and simply vault the iris to a greater degree than is obtainable with lenses currently on the market. Perhaps too much emphasis has been placed on avoiding the endothelium and not enough emphasis on avoiding the iris.

UI MeSH Term Description Entries
D006988 Hyphema Bleeding in the anterior chamber of the eye. Hyphemas
D007910 Lenses, Intraocular Artificial implanted lenses. Implantable Contact Lens,Lens, Intraocular,Contact Lens, Implantable,Intraocular Lens,Intraocular Lenses,Lens, Implantable Contact
D005901 Glaucoma An ocular disease, occurring in many forms, having as its primary characteristics an unstable or a sustained increase in the intraocular pressure which the eye cannot withstand without damage to its structure or impairment of its function. The consequences of the increased pressure may be manifested in a variety of symptoms, depending upon type and severity, such as excavation of the optic disk, hardness of the eyeball, corneal anesthesia, reduced visual acuity, seeing of colored halos around lights, disturbed dark adaptation, visual field defects, and headaches. (Dictionary of Visual Science, 4th ed) Glaucomas
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000867 Anterior Chamber The space in the eye, filled with aqueous humor, bounded anteriorly by the cornea and a small portion of the sclera and posteriorly by a small portion of the ciliary body, the iris, and that part of the crystalline lens which presents through the pupil. (Cline et al., Dictionary of Visual Science, 4th ed, p109) Anterior Chambers,Chamber, Anterior,Chambers, Anterior
D013577 Syndrome A characteristic symptom complex. Symptom Cluster,Cluster, Symptom,Clusters, Symptom,Symptom Clusters,Syndromes
D014605 Uveitis Inflammation of part or all of the uvea, the middle (vascular) tunic of the eye, and commonly involving the other tunics (sclera and cornea, and the retina). (Dorland, 27th ed) Uveitides

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