Biomaterial Database

Experimental suture of the peripheral nerves with "fibrin glue". 1980

R Ventura, and G Torri, and A Campari, and A Giandomenico, and G Peretti

An experiment on rats is presented, concerned with a technique for suturing peripheral nerves by means of "human fibrin glue". The sutures were performed by three different methods: (1) the traditional technique; (2) using a special grooved Vitallium plate (presented by the authors in a previous paper) by means of which all sutures can be dispensed with, and which facilitates more rapid and complete regeneration of the nerve; (3) with "fibrin glue", used on its own or together with the special plate. On comparing the three methods it was found that fibrin glue achieves better approximation of the nerve ends and thus leads to more rapid and more complete regeneration of the peripheral nerve fibres. Combined use with the plate is preferred where there is a minimal loss of nerve substance.

UI	MeSH Term	Description	Entries
D008297	Male		Males
D010525	Peripheral Nerves	The nerves outside of the brain and spinal cord, including the autonomic, cranial, and spinal nerves. Peripheral nerves contain non-neuronal cells and connective tissue as well as axons. The connective tissue layers include, from the outside to the inside, the epineurium, the perineurium, and the endoneurium.	Endoneurium,Epineurium,Perineurium,Endoneuriums,Epineuriums,Nerve, Peripheral,Nerves, Peripheral,Perineuriums,Peripheral Nerve
D005260	Female		Females
D005337	Fibrin	A protein derived from FIBRINOGEN in the presence of THROMBIN, which forms part of the blood clot.	Antithrombin I
D000818	Animals	Unicellular or multicellular, heterotrophic organisms, that have sensation and the power of voluntary movement. Under the older five kingdom paradigm, Animalia was one of the kingdoms. Under the modern three domain model, Animalia represents one of the many groups in the domain EUKARYOTA.	Animal,Metazoa,Animalia
D012584	Sciatic Nerve	A nerve which originates in the lumbar and sacral spinal cord (L4 to S3) and supplies motor and sensory innervation to the lower extremity. The sciatic nerve, which is the main continuation of the sacral plexus, is the largest nerve in the body. It has two major branches, the TIBIAL NERVE and the PERONEAL NERVE.	Nerve, Sciatic,Nerves, Sciatic,Sciatic Nerves
D013536	Suture Techniques	Techniques for securing together the edges of a wound, with loops of thread or similar materials (SUTURES).	Suture Technics,Suture Technic,Suture Technique,Technic, Suture,Technics, Suture,Technique, Suture,Techniques, Suture
D013537	Sutures	Materials used in closing a surgical or traumatic wound. (From Dorland, 28th ed)	Staples, Surgical,Surgical Staples,Staple, Surgical,Surgical Staple,Suture
D014014	Tissue Adhesives	Substances used to cause adherence of tissue to tissue or tissue to non-tissue surfaces, as for prostheses.	Adhesive, Tissue,Adhesives, Tissue,Tissue Adhesive
D014800	Vitallium	An alloy of 60% cobalt, 20% chromium, 5% molybdenum, and traces of other substances. It is used in dentures, certain surgical appliances, prostheses, implants, and instruments.	Cobalt-Chromium-Molybdenum Alloy,Alloy, Cobalt-Chromium-Molybdenum,Cobalt Chromium Molybdenum Alloy