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Para-chloroamphetamine (PCA) produces short-term decreases in eating and drinking. PCA also chronically decreases brain serotonin concentration following a single peripheral injection. The present investigation assessed short- and long-term effects of PCA on ingestive behavior and body weight in greater detail. Following an adaptation period, PCA, 0.0, 1.0, 2.0, 5.0 and 10.0 mg/kg, were administered IP, to free feeding rats. A decrease in food and water consumption was observed during the 0--24 hr postinjection period. During the 24--48 hr period, water consumption was significantly increased compared to baseline. Food intakes during this same period returned to baseline levels. No long-term effects on ingestive behavior or body weight were seen during the following 30 days.
J M Stein, and
M J Wayner, and
K M Kantak, and
R C Cook
July 1976,
Psychopharmacology bulletin,
J M Stein, and
M J Wayner, and
K M Kantak, and
R C Cook
January 1992,
Psychopharmacology,
J M Stein, and
M J Wayner, and
K M Kantak, and
R C Cook
July 1976,
Psychopharmacology bulletin,
J M Stein, and
M J Wayner, and
K M Kantak, and
R C Cook
December 1976,
European journal of pharmacology,
J M Stein, and
M J Wayner, and
K M Kantak, and
R C Cook
June 1995,
Brain research,
J M Stein, and
M J Wayner, and
K M Kantak, and
R C Cook
October 1999,
Experimental animals,
J M Stein, and
M J Wayner, and
K M Kantak, and
R C Cook
June 1978,
Annals of the New York Academy of Sciences,
J M Stein, and
M J Wayner, and
K M Kantak, and
R C Cook
June 1975,
Medical biology,
J M Stein, and
M J Wayner, and
K M Kantak, and
R C Cook
January 1979,
Pharmacology & therapeutics. Part B: General & systematic pharmacology,
J M Stein, and
M J Wayner, and
K M Kantak, and
R C Cook
January 1975,
The Journal of pharmacology and experimental therapeutics,
