BIOMAT Database Logo BIOMAT Database Logo

Tumorigenicity of bay-region diol-epoxides and other benzo-ring derivatives of dibenzo(a,h)pyrene and dibenzo(a,i)pyrene on mouse skin and in newborn mice. 1982

R L Chang, and W Levin, and A W Wood, and R E Lehr, and S Kumar, and H Yagi, and D M Jerina, and A H Conney

UI MeSH Term Description Entries
D009374 Neoplasms, Experimental Experimentally induced new abnormal growth of TISSUES in animals to provide models for studying human neoplasms. Experimental Neoplasms,Experimental Neoplasm,Neoplasm, Experimental
D003043 Cocarcinogenesis The combination of two or more different factors in the production of cancer. Cocarcinogeneses
D004852 Epoxy Compounds Organic compounds that include a cyclic ether with three ring atoms in their structure. They are commonly used as precursors for POLYMERS such as EPOXY RESINS. Epoxide,Epoxides,Epoxy Compound,Oxiranes,Compound, Epoxy,Compounds, Epoxy
D000818 Animals Unicellular or multicellular, heterotrophic organisms, that have sensation and the power of voluntary movement. Under the older five kingdom paradigm, Animalia was one of the kingdoms. Under the modern three domain model, Animalia represents one of the many groups in the domain EUKARYOTA. Animal,Metazoa,Animalia
D000831 Animals, Newborn Refers to animals in the period of time just after birth. Animals, Neonatal,Animal, Neonatal,Animal, Newborn,Neonatal Animal,Neonatal Animals,Newborn Animal,Newborn Animals
D001580 Benzopyrenes A class of chemicals that contain an anthracene ring with a naphthalene ring attached to it. Benzpyrene
D012867 Skin The outer covering of the body that protects it from the environment. It is composed of the DERMIS and the EPIDERMIS.
D012878 Skin Neoplasms Tumors or cancer of the SKIN. Cancer of Skin,Skin Cancer,Cancer of the Skin,Neoplasms, Skin,Cancer, Skin,Cancers, Skin,Neoplasm, Skin,Skin Cancers,Skin Neoplasm
D013329 Structure-Activity Relationship The relationship between the chemical structure of a compound and its biological or pharmacological activity. Compounds are often classed together because they have structural characteristics in common including shape, size, stereochemical arrangement, and distribution of functional groups. Relationship, Structure-Activity,Relationships, Structure-Activity,Structure Activity Relationship,Structure-Activity Relationships
D013997 Time Factors Elements of limited time intervals, contributing to particular results or situations. Time Series,Factor, Time,Time Factor

Related Publications

R L Chang, and W Levin, and A W Wood, and R E Lehr, and S Kumar, and H Yagi, and D M Jerina, and A H Conney
Tumorigenicity of racemic and optically pure bay region diol epoxides and other derivatives of the nitrogen heterocycle dibenz[a,h]acridine on mouse skin.
June 2001, Carcinogenesis,
R L Chang, and W Levin, and A W Wood, and R E Lehr, and S Kumar, and H Yagi, and D M Jerina, and A H Conney
Tumorigenicity of four optically active bay-region 3,4-diol 1, 2-epoxides and other derivatives of the nitrogen heterocycle dibenz[c,h]acridine on mouse skin and in newborn mice.
November 2000, Carcinogenesis,
R L Chang, and W Levin, and A W Wood, and R E Lehr, and S Kumar, and H Yagi, and D M Jerina, and A H Conney
Tumorigenicity in newborn mice of fjord region and other sterically hindered diol epoxides of benzo[g]chrysene, dibenzo[a,l]pyrene (dibenzo[def,p]chrysene), 4H-cyclopenta[def]chrysene and fluoranthene.
November 1995, Carcinogenesis,
R L Chang, and W Levin, and A W Wood, and R E Lehr, and S Kumar, and H Yagi, and D M Jerina, and A H Conney
Tumorigenicity of bay-region epoxides and other derivatives of chrysene and phenanthrene in newborn mice.
December 1979, Cancer research,
R L Chang, and W Levin, and A W Wood, and R E Lehr, and S Kumar, and H Yagi, and D M Jerina, and A H Conney
Enhancing effect of a bay region methyl group on tumorigenicity in newborn mice and mouse skin of enantiomeric bay region diol epoxides formed stereoselectively from methylchrysenes in mouse epidermis.
October 1987, Cancer research,
R L Chang, and W Levin, and A W Wood, and R E Lehr, and S Kumar, and H Yagi, and D M Jerina, and A H Conney
Mutagenicity and tumorigenicity of dihydrodiols, diol epoxides, and other derivatives of benzo(f)quinoline and benzo(h)quinoline.
January 1989, Cancer research,
R L Chang, and W Levin, and A W Wood, and R E Lehr, and S Kumar, and H Yagi, and D M Jerina, and A H Conney
Carcinogenicity of benzo-ring derivatives of benzo(a)pyrene on mouse skin.
September 1977, Cancer research,
R L Chang, and W Levin, and A W Wood, and R E Lehr, and S Kumar, and H Yagi, and D M Jerina, and A H Conney
Tumor-initiating activity on mouse skin of bay region diol-epoxides of 5,6-dimethylchrysene and benzo[c]phenanthrene.
October 1993, Carcinogenesis,
R L Chang, and W Levin, and A W Wood, and R E Lehr, and S Kumar, and H Yagi, and D M Jerina, and A H Conney
Epidermal hyperplasia after topical application of benzo (a) pyrene, benzo (a) pyrene diol epoxides, and other metabolites.
April 1977, Cancer research,
R L Chang, and W Levin, and A W Wood, and R E Lehr, and S Kumar, and H Yagi, and D M Jerina, and A H Conney
The binding to mouse skin DNA of benzo[a]pyrene, its 7,8-diol and 7,8-diol-9,10-epoxides in relation to the tumorigenicity of these compounds.
April 1979, Cancer letters,
Copied contents to your clipboard!