Differential patency and limb salvage for polytetrafluoroethylene and autogenous saphenous vein in severe lower extremity ischemia. 1982

R A Yeager, and R W Hobson, and Z Jamil, and T G Lynch, and B C Lee, and K Jain

Polytetrafluoroethylene (PTFE) was compared to autogenous saphenous vein (ASV) in 133 femoropopliteal and femorotibial or peroneal bypass procedures performed in limb salvage during a 4-year period. PTFE was used as an alternative prosthesis in the absence of a suitable ASV. Sixty-nine femoropopliteal bypasses (FPBPs) were studied--36 with ASV and 33 with PTFE. Sixty-four femorotibial or peroneal bypasses were categorized as femoral distal bypasses (FDBPs)--34 with ASV and 30 with PTFE. With a 3-year clinical follow-up, cumulative function rate (CFR)--patency including thrombectomy--for FPBP with ASV was 65% as compared to 53% for PTFE (P greater than 0.05), whereas the limb salvage rate (LSR) was 75% with ASV and 56% for PTFE (P greater than 0.05). However for FDBP, the GFR was 55% for ASV and 7% for PTFE, whereas the LSR was 55% with ASV and 26% for PTFE. The cumulative patency rate (CPR)--initial thrombosis of a prosthesis as an endpoint--was not significantly (P greater than 0.05) different from CFR, suggesting that thrombectomy with or without distal anastamotic revision does not contribute to patency of the PTFE prosthesis in these limb salvage cases. PTFE was a suitable alternative to ASV for FPBP; however, PTFE is recommended for FDBP in selected cases only.

UI MeSH Term Description Entries
D007511 Ischemia A hypoperfusion of the BLOOD through an organ or tissue caused by a PATHOLOGIC CONSTRICTION or obstruction of its BLOOD VESSELS, or an absence of BLOOD CIRCULATION. Ischemias
D007866 Leg The inferior part of the lower extremity between the KNEE and the ANKLE. Legs
D011138 Polytetrafluoroethylene Homopolymer of tetrafluoroethylene. Nonflammable, tough, inert plastic tubing or sheeting; used to line vessels, insulate, protect or lubricate apparatus; also as filter, coating for surgical implants or as prosthetic material. Synonyms: Fluoroflex; Fluoroplast; Ftoroplast; Halon; Polyfene; PTFE; Tetron. FEP,Fluon,Politef,Polytef,TFE,Teflon,Expanded PTFE,Fluoroplast,GORE-TEX,Goretex,PTFE,Tarflen,GORE TEX,PTFE, Expanded
D012086 Reoperation A repeat operation for the same condition in the same patient due to disease progression or recurrence, or as followup to failed previous surgery. Revision, Joint,Revision, Surgical,Surgery, Repeat,Surgical Revision,Repeat Surgery,Revision Surgery,Joint Revision,Revision Surgeries,Surgery, Revision
D001807 Blood Vessel Prosthesis Device constructed of either synthetic or biological material that is used for the repair of injured or diseased blood vessels. Vascular Prosthesis,Blood Vessel Prostheses,Tissue-Engineered Vascular Graft,Graft, Tissue-Engineered Vascular,Grafts, Tissue-Engineered Vascular,Prostheses, Blood Vessel,Prostheses, Vascular,Prosthesis, Blood Vessel,Prosthesis, Vascular,Tissue Engineered Vascular Graft,Tissue-Engineered Vascular Grafts,Vascular Graft, Tissue-Engineered,Vascular Grafts, Tissue-Engineered,Vascular Prostheses,Vessel Prostheses, Blood,Vessel Prosthesis, Blood
D005500 Follow-Up Studies Studies in which individuals or populations are followed to assess the outcome of exposures, procedures, or effects of a characteristic, e.g., occurrence of disease. Followup Studies,Follow Up Studies,Follow-Up Study,Followup Study,Studies, Follow-Up,Studies, Followup,Study, Follow-Up,Study, Followup
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D012501 Saphenous Vein The vein which drains the foot and leg. Saphenous Veins,Vein, Saphenous,Veins, Saphenous
D014022 Tissue Survival The span of viability of a tissue or an organ. Organ Survival,Organ Viability,Tissue Viability,Survival, Organ,Survival, Tissue,Viability, Organ,Viability, Tissue
D014182 Transplantation, Autologous Transplantation of an individual's own tissue from one site to another site. Autografting,Autologous Transplantation,Autotransplantation,Autograftings,Autologous Transplantations,Autotransplantations,Transplantations, Autologous

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