BIOMAT Database Logo BIOMAT Database Logo

Phenytoin pharmacokinetics: inappropriate data analysis. 1982

T H Grasela, and M E Winter

UI MeSH Term Description Entries
D007700 Kinetics The rate dynamics in chemical or physical systems.
D010672 Phenytoin An anticonvulsant that is used to treat a wide variety of seizures. It is also an anti-arrhythmic and a muscle relaxant. The mechanism of therapeutic action is not clear, although several cellular actions have been described including effects on ion channels, active transport, and general membrane stabilization. The mechanism of its muscle relaxant effect appears to involve a reduction in the sensitivity of muscle spindles to stretch. Phenytoin has been proposed for several other therapeutic uses, but its use has been limited by its many adverse effects and interactions with other drugs. Diphenylhydantoin,Fenitoin,Phenhydan,5,5-Diphenylhydantoin,5,5-diphenylimidazolidine-2,4-dione,Antisacer,Difenin,Dihydan,Dilantin,Epamin,Epanutin,Hydantol,Phenytoin Sodium,Sodium Diphenylhydantoinate,Diphenylhydantoinate, Sodium
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man

Related Publications

T H Grasela, and M E Winter
Population pharmacokinetics of phenytoin from routine clinical data in Japan.
February 1989, Journal of clinical pharmacy and therapeutics,
T H Grasela, and M E Winter
Steady-state pharmacokinetics of phenytoin from routinely collected patient data.
January 1983, Clinical pharmacokinetics,
T H Grasela, and M E Winter
Phenytoin: pharmacokinetics and bioavailability.
February 1976, Clinical pharmacology and therapeutics,
T H Grasela, and M E Winter
Clinical pharmacokinetics of phenytoin.
January 1979, Clinical pharmacokinetics,
T H Grasela, and M E Winter
Replicate analysis of coagulation data? Inappropriate analysis of experimental data.
June 1985, American journal of clinical pathology,
T H Grasela, and M E Winter
Influence on Busilvex pharmacokinetics of clonazepam compared to previous phenytoin historical data.
July 2010, Anticancer research,
T H Grasela, and M E Winter
Population pharmacokinetics of phenytoin from routine clinical data in Japan: an update.
July 1990, Chemical & pharmaceutical bulletin,
T H Grasela, and M E Winter
Pharmacokinetics of phenytoin in children.
November 1981, British journal of clinical pharmacology,
T H Grasela, and M E Winter
Phenytoin pharmacokinetics in catamenial epilepsy.
July 1984, Neurology,
T H Grasela, and M E Winter
Phenytoin pharmacokinetics in therapeutic plasmapheresis.
January 1985, Journal of clinical pharmacology,
Copied contents to your clipboard!