BIOMAT Database Logo BIOMAT Database Logo

UKEMS trial compounds: induction of unscheduled DNA synthesis in HeLa S3 cells. 1982

R H Barrett

UI MeSH Term Description Entries
D008769 Methylnitronitrosoguanidine A nitrosoguanidine derivative with potent mutagenic and carcinogenic properties. Methylnitrosonitroguanidine,Nitrosomethylnitroguanidine,Nitrosonitromethylguanidine,MNNG,N-Methyl-N'-nitro-N-nitrosoguanidine,N Methyl N' nitro N nitrosoguanidine
D009153 Mutagens Chemical agents that increase the rate of genetic mutation by interfering with the function of nucleic acids. A clastogen is a specific mutagen that causes breaks in chromosomes. Clastogen,Clastogens,Genotoxin,Genotoxins,Mutagen
D009154 Mutation Any detectable and heritable change in the genetic material that causes a change in the GENOTYPE and which is transmitted to daughter cells and to succeeding generations. Mutations
D004261 DNA Replication The process by which a DNA molecule is duplicated. Autonomous Replication,Replication, Autonomous,Autonomous Replications,DNA Replications,Replication, DNA,Replications, Autonomous,Replications, DNA
D006367 HeLa Cells The first continuously cultured human malignant CELL LINE, derived from the cervical carcinoma of Henrietta Lacks. These cells are used for, among other things, VIRUS CULTIVATION and PRECLINICAL DRUG EVALUATION assays. Cell, HeLa,Cells, HeLa,HeLa Cell
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D001593 Benzyl Compounds Benzene derivatives that contain a benzyl group with the general formula Phenyl-CH2-R. Compounds, Benzyl
D001713 Biphenyl Compounds Whitish aromatic crystalline organic compounds made up of two conjoined BENZENE rings. Compounds, Biphenyl
D013329 Structure-Activity Relationship The relationship between the chemical structure of a compound and its biological or pharmacological activity. Compounds are often classed together because they have structural characteristics in common including shape, size, stereochemical arrangement, and distribution of functional groups. Relationship, Structure-Activity,Relationships, Structure-Activity,Structure Activity Relationship,Structure-Activity Relationships

Related Publications

R H Barrett
Induction of unscheduled DNA synthesis in HeLa cells by allylic compounds.
October 1983, Cancer letters,
R H Barrett
Spontaneous unscheduled DNA synthesis in GI HeLa cells.
November 1969, Nature,
R H Barrett
The dependence of DNA synthesis on protein synthesis in HeLa S3 cells.
February 1969, Journal of cellular physiology,
R H Barrett
Induction of unscheduled DNA synthesis in human myeloma cells.
February 1980, Blood,
R H Barrett
[Unscheduled DNA synthesis in non-radiation damage to HeLa ZH-63 cells].
July 1971, Tsitologiia,
R H Barrett
Alkaline phosphatase activity in relation to DNA synthesis in synchronized HeLa S3 cells.
October 1973, Experientia,
R H Barrett
Unscheduled DNA synthesis induced by N-methyl-N'-nitro-N-nitrosoguanidine in Hela cells.
February 1982, Gan,
R H Barrett
UKEMS trial compounds: in vitro bacterial mutagenicity.
January 1982, Mutation research,
R H Barrett
[Unscheduled DNA synthesis and repair of HeLa Zh-63 cells sublethally damaged by irradiation].
January 1970, Tsitologiia,
R H Barrett
[Induction of unscheduled DNA synthesis in chromatin in vitro].
April 1976, Doklady Akademii nauk SSSR,
Copied contents to your clipboard!