Pre-exposure rabies immunization of man with suckling mouse brain vaccine. 1982

A M Díaz

A case series study is reported which included serologic results obtained in 195 persons recruited from personnel and trainees of the Pan American Zoonoses Center in Buenos Aires, Argentina, and workers from other institutions. The individuals were vaccinated with three doses of suckling mouse brain vaccine administered on alternate days, and some of them were given a booster dose 30 or 365 days after the primary immunization. The sizeable percentage of reactors with a high neutralizing antibody response in a short period of time, the small number of persons requiring a booster dose 30 days after the first vaccine dose, the rapid and intense secondary immune response and the absence of serious post-vaccinal reactions justify encouraging the use of this abbreviated prophylactic course of suckling mouse brain vaccine.

UI MeSH Term Description Entries
D011818 Rabies Acute VIRAL CNS INFECTION affecting mammals, including humans. It is caused by RABIES VIRUS and usually spread by contamination with virus-laden saliva of bites inflicted by rabid animals. Important animal vectors include the dog, cat, bat, fox, raccoon, skunk, and wolf. Encephalitic Rabies,Furious Rabies,Hydrophobia,Paralytic Rabies,Lyssa,Furious Raby,Lyssas,Rabies, Encephalitic,Rabies, Furious,Raby, Furious
D011819 Rabies Vaccines Vaccines or candidate vaccines used to prevent and treat RABIES. The inactivated virus vaccine is used for preexposure immunization to persons at high risk of exposure, and in conjunction with rabies immunoglobulin, for postexposure prophylaxis. Rabies Human Diploid Cell Vaccine,Rabies Vaccine,Vaccine, Rabies,Vaccines, Rabies
D004306 Dose-Response Relationship, Immunologic A specific immune response elicited by a specific dose of an immunologically active substance or cell in an organism, tissue, or cell. Immunologic Dose-Response Relationship,Relationship, Immunologic Dose-Response,Dose Response Relationship, Immunologic,Dose-Response Relationships, Immunologic,Immunologic Dose Response Relationship,Immunologic Dose-Response Relationships,Relationship, Immunologic Dose Response,Relationships, Immunologic Dose-Response
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000917 Antibody Formation The production of ANTIBODIES by proliferating and differentiated B-LYMPHOCYTES under stimulation by ANTIGENS. Antibody Production,Antibody Response,Antibody Responses,Formation, Antibody,Production, Antibody,Response, Antibody,Responses, Antibody

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