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In 51 patients undergoing elective abdominal surgery, analgesia was provided for the first 24 h after surgery by bolus injections of buprenorphine 0.1 or 0.2 mg given i.v. on patient demand using a patient-operated syringe driver (the "Cardiff" palliator). Excellent analgesia was reported by 47 patients. Four elderly patients had difficulty in operating the demand apparatus. In two other patients, clinically significant ventilatory depression necessitated abandoning the trial. Although there was a high degree of patient and staff acceptance of the method, the potential for ventilatory depression emphasizes the need for close observation of patients receiving i.v. opioids by this technique.
J M Gibbs, and
H D Johnson, and
F M Davis
January 1980,
Acta anaesthesiologica Belgica,
J M Gibbs, and
H D Johnson, and
F M Davis
May 1986,
British journal of anaesthesia,
J M Gibbs, and
H D Johnson, and
F M Davis
January 1995,
Paediatric anaesthesia,
J M Gibbs, and
H D Johnson, and
F M Davis
February 1988,
Der Anaesthesist,
J M Gibbs, and
H D Johnson, and
F M Davis
June 1978,
British journal of anaesthesia,
J M Gibbs, and
H D Johnson, and
F M Davis
April 1985,
Anesthesia and analgesia,
J M Gibbs, and
H D Johnson, and
F M Davis
November 1994,
Masui. The Japanese journal of anesthesiology,
J M Gibbs, and
H D Johnson, and
F M Davis
February 1995,
Masui. The Japanese journal of anesthesiology,
J M Gibbs, and
H D Johnson, and
F M Davis
June 1991,
Ma zui xue za zhi = Anaesthesiologica Sinica,
J M Gibbs, and
H D Johnson, and
F M Davis
November 1981,
Anaesthesia,
