-transparent.png){kind=logo}
The dependency of initial rates of tyramine, tryptamine, serotonin and benzylamine reactions of deamination catalyzed by rat liver monoamine oxidase from its concentrations was studied potentiometrically using an air-gap electrode. The kinetic deamination parameters, i.e. Michaelis constants an maximum velocities, were determined at pH values of 7.6 and 9.0. The inhibition of tyramine deamination at high concentrations of the latter was found for a pH value of 9.0 and the activation of serotonin deamination by its high concentrations for pH values of 7.6 and 9.0. The effects studied may be interpreted in terms of the allosteric nature of MAO.
Related Publications
E B Nikol'skaia, and
O V Iagodina, and
V M Kostrova
August 1979,
Medical biology,
E B Nikol'skaia, and
O V Iagodina, and
V M Kostrova
May 1976,
Biochemical pharmacology,
E B Nikol'skaia, and
O V Iagodina, and
V M Kostrova
April 1979,
Biochemical pharmacology,
E B Nikol'skaia, and
O V Iagodina, and
V M Kostrova
January 1976,
Voprosy meditsinskoi khimii,
E B Nikol'skaia, and
O V Iagodina, and
V M Kostrova
July 1971,
Nihon yakurigaku zasshi. Folia pharmacologica Japonica,
E B Nikol'skaia, and
O V Iagodina, and
V M Kostrova
January 1972,
Advances in biochemical psychopharmacology,
E B Nikol'skaia, and
O V Iagodina, and
V M Kostrova
July 1964,
Experientia,
E B Nikol'skaia, and
O V Iagodina, and
V M Kostrova
January 1963,
Voprosy meditsinskoi khimii,
E B Nikol'skaia, and
O V Iagodina, and
V M Kostrova
January 1989,
Alcohol (Fayetteville, N.Y.),
E B Nikol'skaia, and
O V Iagodina, and
V M Kostrova
January 1968,
Advances in pharmacology,
