Biomaterial Database

Antibodies to the California group of arboviruses in animal populations of New Brunswick. 1982

B L McFarlane, and J E Embree, and J A Embil, and K R Rozee, and A Artsob

Wild and domestic animals of New Brunswick were tested serologically for antibodies to the California group (CAL) of arboviruses. Deer (Odocoileus virginianus) blood collected during 1976 showed 6 of 129 (4.7%) sera with neutralizing antibodies to the snowshoe hare strain (SSH) of CAL. Neutralization tests on moose (Alces alces americana Clinton) sera collected during 1979 indicated 94 of 127 (74%) with antibodies to SSH, 4 of 127 (3.2%) with antibodies to the Jamestown Canyon Strain (JC) of CAL, and 17 of 127 (13.4%) with equal antibody titers to SSH and JC. Hemagglutination inhibition tests on house blood collected during 1977 showed 54 of 204 (26.5%) with antibodies to SSH; of these, 36 also had neutralizing antibodies to SSH. This study is the first indication of CAL activity in New Brunswick and supports evidence of JC activity in northeastern North America.

UI	MeSH Term	Description	Entries
D009500	Neutralization Tests	The measurement of infection-blocking titer of ANTISERA by testing a series of dilutions for a given virus-antiserum interaction end-point, which is generally the dilution at which tissue cultures inoculated with the serum-virus mixtures demonstrate cytopathology (CPE) or the dilution at which 50% of test animals injected with serum-virus mixtures show infectivity (ID50) or die (LD50).	Neutralization Test,Test, Neutralization,Tests, Neutralization
D002043	Bunyaviridae	A family of viruses, mainly arboviruses, consisting of a single strand of RNA. Virions are enveloped particles 90-120 nm diameter. The complete family contains over 300 members arranged in five genera: ORTHOBUNYAVIRUS; HANTAVIRUS; NAIROVIRUS; PHLEBOVIRUS; and TOSPOVIRUS.
D002141	Encephalitis Virus, California	A species in the ORTHOBUNYAVIRUS genus of the family BUNYAVIRIDAE. Serotypes are found in temperate and arctic regions and each is closely associated with a single species of vector mosquito. The vertebrate hosts are usually small mammals but several serotypes infect humans.	Jamestown Canyon virus,Tahyna virus,California Encephalitis Virus,California Encephalitis Viruses,California Group Viruses,California Virus,Encephalitis Viruses, California,La Crosse Encephalitis Virus
D002170	Canada	The largest country in North America, comprising 10 provinces and three territories. Its capital is Ottawa.
D003670	Deer	The family Cervidae of 17 genera and 45 species occurring nearly throughout North America, South America, and Eurasia, on most associated continental islands, and in northern Africa. Wild populations of deer have been established through introduction by people in Cuba, New Guinea, Australia, New Zealand, and other places where the family does not naturally occur. They are slim, long-legged and best characterized by the presence of antlers. Their habitat is forests, swamps, brush country, deserts, and arctic tundra. They are usually good swimmers; some migrate seasonally. (Walker's Mammals of the World, 5th ed, p1362)	Deers
D006385	Hemagglutination Inhibition Tests	Serologic tests in which a known quantity of antigen is added to the serum prior to the addition of a red cell suspension. Reaction result is expressed as the smallest amount of antigen which causes complete inhibition of hemagglutination.	Hemagglutination Inhibition Test,Inhibition Test, Hemagglutination,Inhibition Tests, Hemagglutination,Test, Hemagglutination Inhibition,Tests, Hemagglutination Inhibition
D006736	Horses	Large, hoofed mammals of the family EQUIDAE. Horses are active day and night with most of the day spent seeking and consuming food. Feeding peaks occur in the early morning and late afternoon, and there are several daily periods of rest.	Equus caballus,Equus przewalskii,Horse, Domestic,Domestic Horse,Domestic Horses,Horse,Horses, Domestic
D000818	Animals	Unicellular or multicellular, heterotrophic organisms, that have sensation and the power of voluntary movement. Under the older five kingdom paradigm, Animalia was one of the kingdoms. Under the modern three domain model, Animalia represents one of the many groups in the domain EUKARYOTA.	Animal,Metazoa,Animalia
D000914	Antibodies, Viral	Immunoglobulins produced in response to VIRAL ANTIGENS.	Viral Antibodies