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The effects of TSH treatment (0.1 USPU/kg body weight/die, for 3-4 days) on the blood sugar, serum IRI and circulating FFA responses to glucose and insulin were studied. Blood sugar and serum FFA levels of the dogs, in basal conditions and at any time interval during the test were slightly modified by TSH treatment. The kinetics of insulin disappearance from blood was not affected while the mean serum IRI during the insulin tolerance test was moderately reduced, which suggests that insulin space is moderately raised by TSH. The serum IRI response to glucose (OGTT, IVGTT) was found to be significantly and intensely reduced. The possibility of an inhibitory action of TSH on the insulin response to glucose in dogs, excluding the participation of the thyroid, exerted via insulin space and secretion is discussed.
A Renauld, and
R C Sverdlik, and
L L Andrade, and
R R Rodríguez
January 1975,
Acta diabetologica latina,
A Renauld, and
R C Sverdlik, and
L L Andrade, and
R R Rodríguez
January 1970,
Polskie Archiwum Medycyny Wewnetrznej,
A Renauld, and
R C Sverdlik, and
L L Andrade, and
R R Rodríguez
March 1976,
Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme,
A Renauld, and
R C Sverdlik, and
L L Andrade, and
R R Rodríguez
February 1974,
Nihon Naibunpi Gakkai zasshi,
A Renauld, and
R C Sverdlik, and
L L Andrade, and
R R Rodríguez
July 1968,
Acta paediatrica Scandinavica,
A Renauld, and
R C Sverdlik, and
L L Andrade, and
R R Rodríguez
February 1973,
Metabolism: clinical and experimental,
A Renauld, and
R C Sverdlik, and
L L Andrade, and
R R Rodríguez
August 1957,
Lancet (London, England),
A Renauld, and
R C Sverdlik, and
L L Andrade, and
R R Rodríguez
March 1974,
Medicina,
A Renauld, and
R C Sverdlik, and
L L Andrade, and
R R Rodríguez
September 1969,
The Journal of endocrinology,
A Renauld, and
R C Sverdlik, and
L L Andrade, and
R R Rodríguez
January 1978,
Acta diabetologica latina,
