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It was found that GABA and sodium hydroxybutyrate are capable to prevent gastric ulcers. While protecting the animals from experimental ulcers both the substances display an ability to increase the content of ATP in the gastric wall. ATP that prevents the occurrence of experimental gastric ulcers enhances 14-leucine incorporation into proteins of gastric tissues. It was demonstrated in experiments ulcer prevention that under the effect of 32P-ATP the content of phosphorylated proteins in gastric tissues rises more than 2-fold. This circumstances ensures the increased resistance of the gastric mucosa to the action of proteolytic enzymes. Enhancement of oxygen consumption by the tissues should be also regarded as one of the factors determining high resistance of the mucosa to proteolysis.
A T Tatevosian, and
Zh S Gevorkian, and
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S A Mirzoian
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A T Tatevosian, and
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A T Tatevosian, and
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September 2010,
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A T Tatevosian, and
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A T Tatevosian, and
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A S Oganesian, and
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January 2022,
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A T Tatevosian, and
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A S Oganesian, and
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A T Tatevosian, and
Zh S Gevorkian, and
A S Oganesian, and
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April 1973,
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A T Tatevosian, and
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S A Mirzoian
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A T Tatevosian, and
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A S Oganesian, and
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November 1966,
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A T Tatevosian, and
Zh S Gevorkian, and
A S Oganesian, and
S A Mirzoian
January 1986,
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