Biomaterial Database

Intracranial myospherulosis. 1982

S E Mills, and J R Lininger

A 54-year-old man developed a post-traumatic brain abscess, and antibiotic ointment was instilled into the abscess cavity. The involved tissue was subsequently excised and was shown to contain the characteristic saccules and spherules of myospherulosis. The history of ointment usage further strengthens the association of petrolatum with the development of these structures. This is the first reported case of intracranial myospherulosis.

UI	MeSH Term	Description	Entries
D008297	Male		Males
D008875	Middle Aged	An adult aged 45 - 64 years.	Middle Age
D009823	Ointment Bases	Various mixtures of fats, waxes, animal and plant oils and solid and liquid hydrocarbons; vehicles for medicinal substances intended for external application; there are four classes: hydrocarbon base, absorption base, water-removable base and water-soluble base; several are also emollients.	Bases, Ointment
D010577	Petrolatum	A colloidal system of semisolid hydrocarbons obtained from PETROLEUM. It is used as an ointment base, topical protectant, and lubricant.	Paraffin Jelly,Petroleum Jelly,Petrolatum, Hydrophilic,Petrolatum, White,Vaseline,Hydrophilic Petrolatum,Jelly, Paraffin,Jelly, Petroleum,White Petrolatum
D010592	Pharmaceutic Aids	Substances which are of little or no therapeutic value, but are necessary in the manufacture, compounding, storage, etc., of pharmaceutical preparations or drug dosage forms. They include SOLVENTS, diluting agents, and suspending agents, and emulsifying agents. Also, ANTIOXIDANTS; PRESERVATIVES, PHARMACEUTICAL; COLORING AGENTS; FLAVORING AGENTS; VEHICLES; EXCIPIENTS; OINTMENT BASES.	Aids, Pharmaceutic,Aids, Pharmaceutical,Pharmaceutical Aids
D001927	Brain Diseases	Pathologic conditions affecting the BRAIN, which is composed of the intracranial components of the CENTRAL NERVOUS SYSTEM. This includes (but is not limited to) the CEREBRAL CORTEX; intracranial white matter; BASAL GANGLIA; THALAMUS; HYPOTHALAMUS; BRAIN STEM; and CEREBELLUM.	Intracranial Central Nervous System Disorders,Brain Disorders,CNS Disorders, Intracranial,Central Nervous System Disorders, Intracranial,Central Nervous System Intracranial Disorders,Encephalon Diseases,Encephalopathy,Intracranial CNS Disorders,Brain Disease,Brain Disorder,CNS Disorder, Intracranial,Encephalon Disease,Encephalopathies,Intracranial CNS Disorder
D004913	Erythrocytes, Abnormal	Oxygen-carrying RED BLOOD CELLS in mammalian blood that are abnormal in structure or function.	Abnormal Erythrocytes,Abnormal Erythrocyte,Erythrocyte, Abnormal
D006801	Humans	Members of the species Homo sapiens.	Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D013102	Spherocytes	Small, abnormal spherical red blood cells with more than the normal amount of hemoglobin.	Spherocyte