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Urinary excretion of calcium following an oral calcium loading test in healthy children. 1982

F B Stapleton, and H N Noe, and G Jerkins, and S Roy

The ratio of urinary calcium (UCa)/urinary creatinine (UCr) concentrations (mg/mg) during calcium loading has been used to diagnose hypercalciuric states in adults. The UCa/UCr ratios have been examined before and after an oral dose of calcium in 48 healthy children following five days of abstinence from dietary milk products. No differences in UCa/UCr ratios were observed between sexes, races, or age groups. UCa/UCr ratio before the calcium dose was 0.09 +/- 0.12 (mean +/- 2 SD) and increased to 0.12 +/- 0.15 in urine samples collected for four hours after the calcium load. A direct relationship between UCa/UCr ratio and urinary sodium (UNa)/UCr ratio was observed (r = .57, P less than .01). In six children, calcium loading studies were repeated without prior restriction of dietary calcium. Dietary calcium intake before the calcium loading had little effect upon UCa/UCr ratio before the calcium in these six children (0.068 vs 0.08); however, UCa/UCr values after the calcium load were significantly lower (0.08 vs 0.15) when no dietary calcium restriction preceded the calcium-loading study. These data may allow characterization of renal hypercalciuria and gastrointestinal hyperabsorption of calcium in children with urolithiasis.

UI MeSH Term Description Entries
D008297 Male Males
D012016 Reference Values The range or frequency distribution of a measurement in a population (of organisms, organs or things) that has not been selected for the presence of disease or abnormality. Normal Range,Normal Values,Reference Ranges,Normal Ranges,Normal Value,Range, Normal,Range, Reference,Ranges, Normal,Ranges, Reference,Reference Range,Reference Value,Value, Normal,Value, Reference,Values, Normal,Values, Reference
D002118 Calcium A basic element found in nearly all tissues. It is a member of the alkaline earth family of metals with the atomic symbol Ca, atomic number 20, and atomic weight 40. Calcium is the most abundant mineral in the body and combines with phosphorus to form calcium phosphate in the bones and teeth. It is essential for the normal functioning of nerves and muscles and plays a role in blood coagulation (as factor IV) and in many enzymatic processes. Coagulation Factor IV,Factor IV,Blood Coagulation Factor IV,Calcium-40,Calcium 40,Factor IV, Coagulation
D002648 Child A person 6 to 12 years of age. An individual 2 to 5 years old is CHILD, PRESCHOOL. Children
D002675 Child, Preschool A child between the ages of 2 and 5. Children, Preschool,Preschool Child,Preschool Children
D003404 Creatinine Creatinine Sulfate Salt,Krebiozen,Salt, Creatinine Sulfate,Sulfate Salt, Creatinine
D004032 Diet Regular course of eating and drinking adopted by a person or animal. Diets
D005260 Female Females
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000293 Adolescent A person 13 to 18 years of age. Adolescence,Youth,Adolescents,Adolescents, Female,Adolescents, Male,Teenagers,Teens,Adolescent, Female,Adolescent, Male,Female Adolescent,Female Adolescents,Male Adolescent,Male Adolescents,Teen,Teenager,Youths

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