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A comparative immunochemical study established that heat-stable placental alkaline phosphatase (HPAP) is contained only in malignant epithelium and is not present in the tissues of fetal and definitive uterus. The heterogeneity of HPAP was shown by means of electrophoresis. There is a direct correlation between HPAP level and the degree of tumor differentiation. Immunohistochemical and histochemical studies showed that HPAP occurs in areas of tumor where glandular structure is most pronounced. HPAP secretion in endometrial mucus was observed. An immunochemical test for HPAP is suggested which may be used in evaluating the degree of tumor differentiation and selecting a suitable scheme of treatment. Immunochemical assay of endometrial mucus for HPAP may offer good advantage in mass screenings of females at risk.
M A Volodin, and
A V Afanas'eva, and
Ia V Bokhman, and
O F Chepik, and
E G Shvarev
November 1971,
Lyon medical,
M A Volodin, and
A V Afanas'eva, and
Ia V Bokhman, and
O F Chepik, and
E G Shvarev
May 1985,
The Histochemical journal,
M A Volodin, and
A V Afanas'eva, and
Ia V Bokhman, and
O F Chepik, and
E G Shvarev
November 1971,
Ginecologia y obstetricia de Mexico,
M A Volodin, and
A V Afanas'eva, and
Ia V Bokhman, and
O F Chepik, and
E G Shvarev
October 1983,
Akusherstvo i ginekologiia,
M A Volodin, and
A V Afanas'eva, and
Ia V Bokhman, and
O F Chepik, and
E G Shvarev
March 1971,
Revue francaise de gynecologie et d'obstetrique,
M A Volodin, and
A V Afanas'eva, and
Ia V Bokhman, and
O F Chepik, and
E G Shvarev
January 1986,
Laboratornoe delo,
M A Volodin, and
A V Afanas'eva, and
Ia V Bokhman, and
O F Chepik, and
E G Shvarev
February 1987,
British journal of cancer,
M A Volodin, and
A V Afanas'eva, and
Ia V Bokhman, and
O F Chepik, and
E G Shvarev
September 1964,
Zentralblatt fur Gynakologie,
M A Volodin, and
A V Afanas'eva, and
Ia V Bokhman, and
O F Chepik, and
E G Shvarev
March 1965,
Israel journal of medical sciences,
M A Volodin, and
A V Afanas'eva, and
Ia V Bokhman, and
O F Chepik, and
E G Shvarev
November 1972,
Cancer research,
