BIOMAT Database Logo BIOMAT Database Logo

Colonic polyps in patients with acromegaly. 1982

I Klein, and G Parveen, and J S Gavaler, and D H Vanthiel

Seventeen patients with acromegaly were prospectively studied with barium enemas and colonoscopy to investigate the possibility that acromegaly is associated with an increased frequency of colonic polyps and colon cancer. Polyps were identified in nine patients and were removed and examined in eight. In five patients the polyps were adenomatous, and in four of the five there were multiple polyps. The presence of polyps closely correlated with the presence of skin tags (p = 0.041) and also with the age of the patient (p less than 0.01). No new cases of colonic cancer were discovered; however, reviewing the records of 44 patients with acromegaly, four cases were previously diagnosed with colon carcinoma. This study identifies a unique group of patients that are at risk for the development of colonic polyps and perhaps colon cancer.

UI MeSH Term Description Entries
D006965 Hyperplasia An increase in the number of cells in a tissue or organ without tumor formation. It differs from HYPERTROPHY, which is an increase in bulk without an increase in the number of cells. Hyperplasias
D007417 Intestinal Polyps Discrete abnormal tissue masses that protrude into the lumen of the INTESTINE. A polyp is attached to the intestinal wall either by a stalk, pedunculus, or by a broad base. Intestinal Polyp,Polyp, Intestinal,Polyps, Intestinal
D008297 Male Males
D008875 Middle Aged An adult aged 45 - 64 years. Middle Age
D011446 Prospective Studies Observation of a population for a sufficient number of persons over a sufficient number of years to generate incidence or mortality rates subsequent to the selection of the study group. Prospective Study,Studies, Prospective,Study, Prospective
D003110 Colonic Neoplasms Tumors or cancer of the COLON. Cancer of Colon,Colon Adenocarcinoma,Colon Cancer,Cancer of the Colon,Colon Neoplasms,Colonic Cancer,Neoplasms, Colonic,Adenocarcinoma, Colon,Adenocarcinomas, Colon,Cancer, Colon,Cancer, Colonic,Cancers, Colon,Cancers, Colonic,Colon Adenocarcinomas,Colon Cancers,Colon Neoplasm,Colonic Cancers,Colonic Neoplasm,Neoplasm, Colon,Neoplasm, Colonic,Neoplasms, Colon
D005260 Female Females
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000172 Acromegaly A condition caused by prolonged exposure to excessive HUMAN GROWTH HORMONE in adults. It is characterized by bony enlargement of the FACE; lower jaw (PROGNATHISM); hands; FEET; HEAD; and THORAX. The most common etiology is a GROWTH HORMONE-SECRETING PITUITARY ADENOMA. (From Joynt, Clinical Neurology, 1992, Ch36, pp79-80) Inappropriate Growth Hormone Secretion Syndrome (Acromegaly),Somatotropin Hypersecretion Syndrome (Acromegaly),Inappropriate GH Secretion Syndrome (Acromegaly),Hypersecretion Syndrome, Somatotropin (Acromegaly),Hypersecretion Syndromes, Somatotropin (Acromegaly),Somatotropin Hypersecretion Syndromes (Acromegaly),Syndrome, Somatotropin Hypersecretion (Acromegaly),Syndromes, Somatotropin Hypersecretion (Acromegaly)
D000236 Adenoma A benign epithelial tumor with a glandular organization. Adenoma, Basal Cell,Adenoma, Follicular,Adenoma, Microcystic,Adenoma, Monomorphic,Adenoma, Papillary,Adenoma, Trabecular,Adenomas,Adenomas, Basal Cell,Adenomas, Follicular,Adenomas, Microcystic,Adenomas, Monomorphic,Adenomas, Papillary,Adenomas, Trabecular,Basal Cell Adenoma,Basal Cell Adenomas,Follicular Adenoma,Follicular Adenomas,Microcystic Adenoma,Microcystic Adenomas,Monomorphic Adenoma,Monomorphic Adenomas,Papillary Adenoma,Papillary Adenomas,Trabecular Adenoma,Trabecular Adenomas

Related Publications

I Klein, and G Parveen, and J S Gavaler, and D H Vanthiel
Colonic polyps in acromegaly.
August 1991, Annals of internal medicine,
I Klein, and G Parveen, and J S Gavaler, and D H Vanthiel
Neoplastic colonic polyps in acromegaly.
December 1994, Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme,
I Klein, and G Parveen, and J S Gavaler, and D H Vanthiel
Acromegaly, colonic polyps and carcinoma.
July 1997, Clinical endocrinology,
I Klein, and G Parveen, and J S Gavaler, and D H Vanthiel
[Virtual colonoscopy, colonic polyps and acromegaly].
January 2009, Arquivos de gastroenterologia,
I Klein, and G Parveen, and J S Gavaler, and D H Vanthiel
High prevalence of colonic polyps in patients with acromegaly. Influence of sex and age.
June 1994, Archives of internal medicine,
I Klein, and G Parveen, and J S Gavaler, and D H Vanthiel
Acromegaly with cavernous haemangioma of the liver and colonic polyps.
September 1995, Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme,
I Klein, and G Parveen, and J S Gavaler, and D H Vanthiel
Serum biomarkers of colonic polyps in patients with acromegaly: a meta-analysis and systematic review.
February 2023, Pituitary,
I Klein, and G Parveen, and J S Gavaler, and D H Vanthiel
Prevalence of colonic polyps is not increased in patients with acromegaly: analysis of 60 patients from India.
March 2004, Journal of gastroenterology and hepatology,
I Klein, and G Parveen, and J S Gavaler, and D H Vanthiel
Clinical Characteristics and Associated Factors of Colonic Polyps in Acromegaly.
November 2022, Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association,
I Klein, and G Parveen, and J S Gavaler, and D H Vanthiel
[Gastrointestinal tract polyps in acromegaly patients].
January 2010, Przeglad lekarski,
Copied contents to your clipboard!