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Clinical vitreous fluorophotometry is a technique used to evaluate the early breakdown of the blood-retina barrier, which is often seen in diabetic retinopathy. However, the test does not take into account the possibility of individual variations of fluorescein diffusion in the vitreous body. This study undertook to follow the diffusion of a fluorescein solution in 20 different bovine vitreous bodies in a laboratory setting. The results showed a broad distribution of fluorescein diffusion in the sampled population. By statistical analysis, at least three subgroups, differing with respect to the fluorescein dye diffusion pattern, were identified. Further experiments suggest that variation in hyaluronic acid structure in vitreous bodies might account for these differences.
S Ross, and
R Arffa, and
D Miller, and
J N Weiss, and
B J Ransil
January 1981,
Transactions of the ophthalmological societies of the United Kingdom,
S Ross, and
R Arffa, and
D Miller, and
J N Weiss, and
B J Ransil
August 1987,
Archives of ophthalmology (Chicago, Ill. : 1960),
S Ross, and
R Arffa, and
D Miller, and
J N Weiss, and
B J Ransil
July 1988,
Journal of the Royal Society of Medicine,
S Ross, and
R Arffa, and
D Miller, and
J N Weiss, and
B J Ransil
May 1982,
[Zhonghua yan ke za zhi] Chinese journal of ophthalmology,
S Ross, and
R Arffa, and
D Miller, and
J N Weiss, and
B J Ransil
January 1980,
Acta endocrinologica. Supplementum,
S Ross, and
R Arffa, and
D Miller, and
J N Weiss, and
B J Ransil
January 1985,
Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie,
S Ross, and
R Arffa, and
D Miller, and
J N Weiss, and
B J Ransil
January 1985,
Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie,
S Ross, and
R Arffa, and
D Miller, and
J N Weiss, and
B J Ransil
February 1983,
American journal of ophthalmology,
S Ross, and
R Arffa, and
D Miller, and
J N Weiss, and
B J Ransil
January 1979,
Ophthalmology,
S Ross, and
R Arffa, and
D Miller, and
J N Weiss, and
B J Ransil
January 1981,
Developments in ophthalmology,
