-transparent.png){kind=logo}
The salt dependence of the iron-binding properties of transferrin was studied by urea/polyacrylamide-gel electrophoresis. The distribution of iron between the N-terminal and C-terminal binding sites under equilibrium conditions and the rates of release of iron from the two sites were studied. It was found that salt increases the thermodynamic stability of iron binding in the N-terminal site relative to the C-terminal site. Similar behaviour is observed for the kinetics of iron release, where salt retards the rate of removal of iron from the N-terminal site but facilitates removal from the C-terminal site.
Related Publications
J Williams, and
N D Chasteen, and
K Moreton
November 1967,
Biochemistry,
J Williams, and
N D Chasteen, and
K Moreton
January 2003,
Clinical chemistry,
J Williams, and
N D Chasteen, and
K Moreton
October 1994,
Journal of cellular physiology,
J Williams, and
N D Chasteen, and
K Moreton
October 2002,
Clinical chemistry and laboratory medicine,
J Williams, and
N D Chasteen, and
K Moreton
July 1995,
The Biochemical journal,
J Williams, and
N D Chasteen, and
K Moreton
July 1984,
Proceedings of the National Academy of Sciences of the United States of America,
J Williams, and
N D Chasteen, and
K Moreton
February 1985,
Singapore medical journal,
J Williams, and
N D Chasteen, and
K Moreton
September 2005,
Biochimica et biophysica acta,
J Williams, and
N D Chasteen, and
K Moreton
September 1994,
British journal of haematology,
J Williams, and
N D Chasteen, and
K Moreton
May 2017,
The journal of physical chemistry. B,
