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The response of serum calcium, PTH, CT and gastrin to an infusion of secretin (3 CU/kg/h) over a period of 90 min was studied in ten healthy males and two female patients with hypoparathyroidism. In the healthy males serum calcium, after a transient fall, significantly increased at 45 min after the onset of the infusion (P less than 0.001). Serum iPTH rose significantly within 5 min whereas serum CT and gastrin concentrations did not change. The two hypoparathyroid patients did not show any variations in either serum iPTH or calcium. These findings suggest that infusion of pharmacological doses of secretin into normal subjects modifies serum calcium, and that this change is due to PTH release.
V Lo Cascio, and
W Piubello, and
L Cominacini, and
I Vantini, and
G Galvanini, and
A Ederle, and
G Cavallini, and
L A Scuro
September 1977,
Clinical endocrinology,
V Lo Cascio, and
W Piubello, and
L Cominacini, and
I Vantini, and
G Galvanini, and
A Ederle, and
G Cavallini, and
L A Scuro
July 1987,
South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde,
V Lo Cascio, and
W Piubello, and
L Cominacini, and
I Vantini, and
G Galvanini, and
A Ederle, and
G Cavallini, and
L A Scuro
March 1977,
Gut,
V Lo Cascio, and
W Piubello, and
L Cominacini, and
I Vantini, and
G Galvanini, and
A Ederle, and
G Cavallini, and
L A Scuro
January 1993,
European journal of clinical pharmacology,
V Lo Cascio, and
W Piubello, and
L Cominacini, and
I Vantini, and
G Galvanini, and
A Ederle, and
G Cavallini, and
L A Scuro
January 1980,
Scandinavian journal of gastroenterology,
V Lo Cascio, and
W Piubello, and
L Cominacini, and
I Vantini, and
G Galvanini, and
A Ederle, and
G Cavallini, and
L A Scuro
October 1975,
Archives of surgery (Chicago, Ill. : 1960),
V Lo Cascio, and
W Piubello, and
L Cominacini, and
I Vantini, and
G Galvanini, and
A Ederle, and
G Cavallini, and
L A Scuro
November 1983,
Scandinavian journal of clinical and laboratory investigation,
V Lo Cascio, and
W Piubello, and
L Cominacini, and
I Vantini, and
G Galvanini, and
A Ederle, and
G Cavallini, and
L A Scuro
March 1989,
American journal of hypertension,
V Lo Cascio, and
W Piubello, and
L Cominacini, and
I Vantini, and
G Galvanini, and
A Ederle, and
G Cavallini, and
L A Scuro
October 1967,
The American journal of physiology,
V Lo Cascio, and
W Piubello, and
L Cominacini, and
I Vantini, and
G Galvanini, and
A Ederle, and
G Cavallini, and
L A Scuro
August 1980,
The Journal of clinical endocrinology and metabolism,
