-transparent.png){kind=logo}
Enzyme-linked immunosorbent assay (ELISA) was developed for IgM, IgA and IgG antibodies against purified protein derivative of tuberculin (PPD). PPD antibodies of 44 patients with active pulmonary tuberculosis were measured at admission to hospital. The control material consisted of 35 healthy blood donors. The mean antibody levels in all three immunoglobulin classes correlated to the extent of the tuberculous infection, i.e. the severer the disease the higher the mean antibody level. The mean antibody levels also were significantly higher in the tuberculosis patients than in the controls, the only exception was specific IgA antibodies in the patients with minimal disease. ELISA-positivity of the patients, i.e. positive result in at least one immunoglobulin class was as follows: 33% of the grade I, 64% of the grade II and 100% of the grade II patients.
M K Viljanen, and
J Eskola, and
E Tala
January 1984,
Bulletin of the World Health Organization,
M K Viljanen, and
J Eskola, and
E Tala
November 1984,
The American review of respiratory disease,
M K Viljanen, and
J Eskola, and
E Tala
December 1984,
Kekkaku : [Tuberculosis],
M K Viljanen, and
J Eskola, and
E Tala
January 1990,
Kekkaku : [Tuberculosis],
M K Viljanen, and
J Eskola, and
E Tala
February 1987,
Clinica chimica acta; international journal of clinical chemistry,
M K Viljanen, and
J Eskola, and
E Tala
July 1987,
Tropical and geographical medicine,
M K Viljanen, and
J Eskola, and
E Tala
April 1987,
Kekkaku : [Tuberculosis],
M K Viljanen, and
J Eskola, and
E Tala
November 1983,
Zentralblatt fur Bakteriologie, Mikrobiologie, und Hygiene. Series A, Medical microbiology, infectious diseases, virology, parasitology,
M K Viljanen, and
J Eskola, and
E Tala
September 1980,
Tubercle,
M K Viljanen, and
J Eskola, and
E Tala
January 1982,
Scandinavian journal of infectious diseases,
