An anatomical investigation of projections from lateral geniculate nucleus to visual cortical areas 17 and 18 in newborn kitten. 1982

Z Henderson

The presence of projections from the lateral geniculate nucleus to visual cortical areas 17 and 18 in newborn kitten was examined using the method of retrograde axonal transport. An injection of either horseradish peroxidase (HRP) or horseradish peroxidase conjugated to wheat germ agglutinin (HRP-WGA) was made into area 17 on one side of the brain and area 18 on the other side. The results were not unlike those from experiments on adults. Area 17 injections label a relatively high proportion of cells in laminae A and A1 and the distribution of sizes of labelled cells is almost the same as that for the total cell population. Area 18 injections label only a small percentage of the total cell population in laminae A and A1 and most of the labelled cells are large. Cells in the C layers are labelled after an injection into either area 17 or 18. It was concluded that the formation of organized thalamocortical projections in the kitten does not rely on visual experience as the projections are already present at birth.

UI MeSH Term Description Entries
D009474 Neurons The basic cellular units of nervous tissue. Each neuron consists of a body, an axon, and dendrites. Their purpose is to receive, conduct, and transmit impulses in the NERVOUS SYSTEM. Nerve Cells,Cell, Nerve,Cells, Nerve,Nerve Cell,Neuron
D012160 Retina The ten-layered nervous tissue membrane of the eye. It is continuous with the OPTIC NERVE and receives images of external objects and transmits visual impulses to the brain. Its outer surface is in contact with the CHOROID and the inner surface with the VITREOUS BODY. The outer-most layer is pigmented, whereas the inner nine layers are transparent. Ora Serrata
D002415 Cats The domestic cat, Felis catus, of the carnivore family FELIDAE, comprising over 30 different breeds. The domestic cat is descended primarily from the wild cat of Africa and extreme southwestern Asia. Though probably present in towns in Palestine as long ago as 7000 years, actual domestication occurred in Egypt about 4000 years ago. (From Walker's Mammals of the World, 6th ed, p801) Felis catus,Felis domesticus,Domestic Cats,Felis domestica,Felis sylvestris catus,Cat,Cat, Domestic,Cats, Domestic,Domestic Cat
D002454 Cell Differentiation Progressive restriction of the developmental potential and increasing specialization of function that leads to the formation of specialized cells, tissues, and organs. Differentiation, Cell,Cell Differentiations,Differentiations, Cell
D005829 Geniculate Bodies Part of the DIENCEPHALON inferior to the caudal end of the dorsal THALAMUS. Includes the lateral geniculate body which relays visual impulses from the OPTIC TRACT to the calcarine cortex, and the medial geniculate body which relays auditory impulses from the lateral lemniscus to the AUDITORY CORTEX. Lateral Geniculate Body,Medial Geniculate Body,Metathalamus,Corpus Geniculatum Mediale,Geniculate Nucleus,Lateral Geniculate Nucleus,Medial Geniculate Complex,Medial Geniculate Nucleus,Nucleus Geniculatus Lateralis Dorsalis,Nucleus Geniculatus Lateralis Pars Dorsalis,Bodies, Geniculate,Complex, Medial Geniculate,Complices, Medial Geniculate,Corpus Geniculatum Mediales,Geniculate Bodies, Lateral,Geniculate Bodies, Medial,Geniculate Body,Geniculate Body, Lateral,Geniculate Body, Medial,Geniculate Complex, Medial,Geniculate Complices, Medial,Geniculate Nucleus, Lateral,Geniculate Nucleus, Medial,Geniculatum Mediale, Corpus,Geniculatum Mediales, Corpus,Lateral Geniculate Bodies,Medial Geniculate Bodies,Medial Geniculate Complices,Mediale, Corpus Geniculatum,Mediales, Corpus Geniculatum,Nucleus, Geniculate,Nucleus, Lateral Geniculate,Nucleus, Medial Geniculate
D006735 Horseradish Peroxidase An enzyme isolated from horseradish which is able to act as an antigen. It is frequently used as a histochemical tracer for light and electron microscopy. Its antigenicity has permitted its use as a combined antigen and marker in experimental immunology. Alpha-Peroxidase,Ferrihorseradish Peroxidase,Horseradish Peroxidase II,Horseradish Peroxidase III,Alpha Peroxidase,II, Horseradish Peroxidase,III, Horseradish Peroxidase,Peroxidase II, Horseradish,Peroxidase III, Horseradish,Peroxidase, Ferrihorseradish,Peroxidase, Horseradish
D000818 Animals Unicellular or multicellular, heterotrophic organisms, that have sensation and the power of voluntary movement. Under the older five kingdom paradigm, Animalia was one of the kingdoms. Under the modern three domain model, Animalia represents one of the many groups in the domain EUKARYOTA. Animal,Metazoa,Animalia
D000831 Animals, Newborn Refers to animals in the period of time just after birth. Animals, Neonatal,Animal, Neonatal,Animal, Newborn,Neonatal Animal,Neonatal Animals,Newborn Animal,Newborn Animals
D001369 Axons Nerve fibers that are capable of rapidly conducting impulses away from the neuron cell body. Axon
D012183 Retrograde Degeneration Pathologic changes that occur in the axon and cell body of a neuron proximal to an axonal lesion. The process is characterized by central chromatolysis which features flattening and displacement of the nucleus, loss of Nissl bodies, and cellular edema. Central chromatolysis primarily occurs in lower motor neurons. Axon Reaction,Nissl Degeneration,Retrograde Degeneration, Transneuronal,Axonal Reaction,Trans-Synaptic Degeneration,Axon Reactions,Axonal Reactions,Degeneration, Nissl,Degeneration, Retrograde,Degeneration, Trans-Synaptic,Degeneration, Transneuronal Retrograde,Degenerations, Retrograde,Degenerations, Trans-Synaptic,Degenerations, Transneuronal Retrograde,Reaction, Axon,Reaction, Axonal,Reactions, Axon,Reactions, Axonal,Retrograde Degenerations,Retrograde Degenerations, Transneuronal,Trans Synaptic Degeneration,Trans-Synaptic Degenerations,Transneuronal Retrograde Degeneration,Transneuronal Retrograde Degenerations

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