Biomaterial Database

Gas chromatographic determination of 1,2-propanediol dinitrate in blood. 1982

S D Erk, and C H Jarboe, and P E Newton, and C Pfledderer

A method is described for determination of 1,2-propanediol dinitrate in blood at concentrations ranging from 10 ng/ml up to 25,000 ng/ml. It used double ether extraction with manual shaking in order to complete sample preparation within 5 min. Samples are analyzed via gas chromatography-electron-capture detection using a column of 3% base deactivated SP-2250 on Supelcoport. This column provides excellent separation and little 1,2-propanediol dinitrate tailing.

UI	MeSH Term	Description	Entries
D011409	Propylene Glycols	Derivatives of propylene glycol (1,2-propanediol). They are used as humectants and solvents in pharmaceutical preparations.	Propanediols,Glycols, Propylene
D012016	Reference Values	The range or frequency distribution of a measurement in a population (of organisms, organs or things) that has not been selected for the presence of disease or abnormality.	Normal Range,Normal Values,Reference Ranges,Normal Ranges,Normal Value,Range, Normal,Range, Reference,Ranges, Normal,Ranges, Reference,Reference Range,Reference Value,Value, Normal,Value, Reference,Values, Normal,Values, Reference
D002849	Chromatography, Gas	Fractionation of a vaporized sample as a consequence of partition between a mobile gaseous phase and a stationary phase held in a column. Two types are gas-solid chromatography, where the fixed phase is a solid, and gas-liquid, in which the stationary phase is a nonvolatile liquid supported on an inert solid matrix.	Chromatography, Gas-Liquid,Gas Chromatography,Chromatographies, Gas,Chromatographies, Gas-Liquid,Chromatography, Gas Liquid,Gas Chromatographies,Gas-Liquid Chromatographies,Gas-Liquid Chromatography
D006801	Humans	Members of the species Homo sapiens.	Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man