False positive, 'atypical ring' pregnancy tests were identified in 14 patients with systemic lupus erythematosus. The abnormality was associated with heavy proteinuria in 8 patients, menopause or drug-induced amenorrhea in 4 patients, and actual pregnancy in one patient. Serum levels of human chorionic gonadotropin were normal in 13 patients and elevated in the single patient with a true pregnancy.