BIOMAT Database Logo BIOMAT Database Logo

Enhancing effect of saccharated ferric oxide on human lymphocyte transformation in serum-free medium. 1982

Y Tanno, and T Takishima

The effect of saccharated ferric oxide on the response of human peripheral lymphocytes to stimulation by phytohemagglutinin in serum-free medium was studied by measuring the incorporation of [3H]thymidine into DNA. The addition of saccharated ferric oxide resulted in a significant increase in [3H]thymidine uptake not only with mitogen added, but also without mitogen, suggesting that this compound itself was mitogenic.

UI MeSH Term Description Entries
D007501 Iron A metallic element with atomic symbol Fe, atomic number 26, and atomic weight 55.85. It is an essential constituent of HEMOGLOBINS; CYTOCHROMES; and IRON-BINDING PROTEINS. It plays a role in cellular redox reactions and in the transport of OXYGEN. Iron-56,Iron 56
D008213 Lymphocyte Activation Morphologic alteration of small B LYMPHOCYTES or T LYMPHOCYTES in culture into large blast-like cells able to synthesize DNA and RNA and to divide mitotically. It is induced by INTERLEUKINS; MITOGENS such as PHYTOHEMAGGLUTININS, and by specific ANTIGENS. It may also occur in vivo as in GRAFT REJECTION. Blast Transformation,Blastogenesis,Lymphoblast Transformation,Lymphocyte Stimulation,Lymphocyte Transformation,Transformation, Blast,Transformation, Lymphoblast,Transformation, Lymphocyte,Activation, Lymphocyte,Stimulation, Lymphocyte
D002478 Cells, Cultured Cells propagated in vitro in special media conducive to their growth. Cultured cells are used to study developmental, morphologic, metabolic, physiologic, and genetic processes, among others. Cultured Cells,Cell, Cultured,Cultured Cell
D004261 DNA Replication The process by which a DNA molecule is duplicated. Autonomous Replication,Replication, Autonomous,Autonomous Replications,DNA Replications,Replication, DNA,Replications, Autonomous,Replications, DNA
D005290 Ferric Compounds Inorganic or organic compounds containing trivalent iron. Compounds, Ferric
D005937 Glucaric Acid A sugar acid derived from D-glucose in which both the aldehydic carbon atom and the carbon atom bearing the primary hydroxyl group are oxidized to carboxylic acid groups. Glucosaccharic Acid,L-Gularic Acid,Levo-Gularic Acid,Tetrahydroxyadipic Acid,Calcium Glucarate,Calcium Glucarate, Anhydrous,Calcium Saccharate,Calcium Saccharate Anhydrous,Calcium Saccharate Tetrahydrate,Calcium Saccharate, Anhydrous,D-Glucaric Acid,D-Saccharic Acid,Saccharic Acid,Acid, Saccharic,Anhydrous Calcium Glucarate,Anhydrous Calcium Saccharate,D Glucaric Acid,D Saccharic Acid,Glucarate, Anhydrous Calcium,Glucarate, Calcium,L Gularic Acid,Levo Gularic Acid,Saccharate Tetrahydrate, Calcium,Saccharate, Anhydrous Calcium,Saccharate, Calcium,Tetrahydrate, Calcium Saccharate
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000077605 Ferric Oxide, Saccharated A glucaric acid-iron conjugate that is used in the treatment of IRON-DEFICIENCY ANEMIA, including in patients with chronic kidney disease, when oral iron therapy is ineffective or impractical. D-Glucaric acid, iron(2+) salt (1:1),Ferri-Saccharate,Ferric Saccharate,Hippiron,Iron Oxide (Saccharated),Iron Sucrose,Iron(III)-Hydroxide Sucrose Complex,Iron-Saccharate,Venofer,Ferri Saccharate,Iron Saccharate,Saccharated Ferric Oxide

Related Publications

Y Tanno, and T Takishima
[Knowledge on injectible saccharated ferric oxide].
September 1956, Dansk tidsskrift for farmaci,
Y Tanno, and T Takishima
[Information on injectable saccharated ferric oxide].
November 1956, Pharmaceutica acta Helvetiae,
Y Tanno, and T Takishima
Effect of intravenous saccharated ferric oxide on serum FGF23 and mineral metabolism in hemodialysis patients.
January 2011, American journal of nephrology,
Y Tanno, and T Takishima
Lymphokine production and lymphocyte transformation by human mononuclear cells in a serum-free medium.
October 1983, Journal of immunological methods,
Y Tanno, and T Takishima
Effect of saccharated ferric oxide and iron dextran on the metabolism of phosphorus in rats.
July 2005, The Journal of laboratory and clinical medicine,
Y Tanno, and T Takishima
[Case of osteomalacia due to intravenous saccharated ferric oxide].
July 1998, Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine,
Y Tanno, and T Takishima
Mitogen-induced human lymphocyte activation in serum-free medium.
April 1973, Clinical immunology and immunopathology,
Y Tanno, and T Takishima
Iatrogenic osteomalacia caused by intravenous administration of saccharated ferric oxide.
May 1993, American journal of hematology,
Y Tanno, and T Takishima
Lymphocyte culture in serum-free medium.
April 1971, Lancet (London, England),
Y Tanno, and T Takishima
Oral Ferric Citrate Hydrate Associated With Less Oxidative Stress Than Intravenous Saccharated Ferric Oxide.
March 2018, Kidney international reports,
Copied contents to your clipboard!