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Detection of opiates in urine by means of thin-layer immunoassay. 1982

M E Fredenburg, and N T Lappas

The use of thin-layer immunoassay (TIA) for the direct detection of opiates in unextracted urine is described. This novel immunoassay is capable of detecting less than 1 ng of opiates, rapidly and inexpensively, without the use of radioactive materials or sophisticated analytical instrumentation. The method was evaluated in a study of 68 post mortem urines and found to be reliable for the detection of opiates in this type of sample.

UI MeSH Term Description Entries
D007118 Immunoassay A technique using antibodies for identifying or quantifying a substance. Usually the substance being studied serves as antigen both in antibody production and in measurement of antibody by the test substance. Immunochromatographic Assay,Assay, Immunochromatographic,Assays, Immunochromatographic,Immunoassays,Immunochromatographic Assays
D009294 Narcotics Agents that induce NARCOSIS. Narcotics include agents that cause somnolence or induced sleep (STUPOR); natural or synthetic derivatives of OPIUM or MORPHINE or any substance that has such effects. They are potent inducers of ANALGESIA and OPIOID-RELATED DISORDERS. Analgesics, Narcotic,Narcotic Analgesics,Narcotic,Narcotic Effect,Narcotic Effects,Effect, Narcotic,Effects, Narcotic
D005554 Forensic Medicine The application of medical knowledge to questions of law. Legal Medicine,Medicine, Forensic,Medicine, Legal

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