Failure of peak expiratory flow rate to predict hospital admission in acute asthma. 1982

T G Martin, and R M Elenbaas, and S H Pingleton

Our study evaluated the ability of early peak expiratory flow rates (PEFR) to be predictive of hospital admission while double blinding the measurements and using a standardized treatment protocol and specific admission criteria. The measurements were recorded prior to and after initial therapy. Eighty-six acute asthmatic episodes in 51 patients were analyzed. Nine (10.5%) of the episodes resulted in hospitalization; 77 (89.5%) resulted in discharge. No correlation with admission was found for the initial PEFR, a second PEFR following treatment, or the differences between these two values. Our study indicates that early PEFRs alone are not useful predictors of the need for hospital admission. Although a significant number of patients in our study population presented with severe airflow obstruction, they responded sufficiently to treatment to permit discharge.

UI MeSH Term Description Entries
D008297 Male Males
D010366 Peak Expiratory Flow Rate Measurement of the maximum rate of airflow attained during a FORCED VITAL CAPACITY determination. Common abbreviations are PEFR and PFR. Expiratory Peak Flow Rate,Flow Rate, Peak Expiratory,PEFR
D011379 Prognosis A prediction of the probable outcome of a disease based on a individual's condition and the usual course of the disease as seen in similar situations. Prognostic Factor,Prognostic Factors,Factor, Prognostic,Factors, Prognostic,Prognoses
D004311 Double-Blind Method A method of studying a drug or procedure in which both the subjects and investigators are kept unaware of who is actually getting which specific treatment. Double-Masked Study,Double-Blind Study,Double-Masked Method,Double Blind Method,Double Blind Study,Double Masked Method,Double Masked Study,Double-Blind Methods,Double-Blind Studies,Double-Masked Methods,Double-Masked Studies,Method, Double-Blind,Method, Double-Masked,Methods, Double-Blind,Methods, Double-Masked,Studies, Double-Blind,Studies, Double-Masked,Study, Double-Blind,Study, Double-Masked
D004837 Epinephrine The active sympathomimetic hormone from the ADRENAL MEDULLA. It stimulates both the alpha- and beta- adrenergic systems, causes systemic VASOCONSTRICTION and gastrointestinal relaxation, stimulates the HEART, and dilates BRONCHI and cerebral vessels. It is used in ASTHMA and CARDIAC FAILURE and to delay absorption of local ANESTHETICS. Adrenaline,4-(1-Hydroxy-2-(methylamino)ethyl)-1,2-benzenediol,Adrenaline Acid Tartrate,Adrenaline Bitartrate,Adrenaline Hydrochloride,Epifrin,Epinephrine Acetate,Epinephrine Bitartrate,Epinephrine Hydrochloride,Epinephrine Hydrogen Tartrate,Epitrate,Lyophrin,Medihaler-Epi,Acetate, Epinephrine
D005260 Female Females
D005540 Forced Expiratory Flow Rates The rate of airflow measured during a FORCED VITAL CAPACITY determination. Expiratory Forced Flow Rates,Flow Rates, Expiratory Forced,Flow Rates, Forced Expiratory
D006760 Hospitalization The confinement of a patient in a hospital. Hospitalizations
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000208 Acute Disease Disease having a short and relatively severe course. Acute Diseases,Disease, Acute,Diseases, Acute

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