Biomaterial Database

Family functioning as a mediating variable affecting psychosocial adjustment of children with cystic fibrosis. 1982

B L Lewis, and K T Khaw

Family functioning was examined as a mediating variable affecting adjustment in children with cystic fibrosis. Three groups of children (cystic fibrosis, asthma, and healthy control subjects) were initially compared on two dimensions of adjustment: self-concept and frequency of behavior problems. The families of these children were compared according to functional level of "cohesion" and "adaptability" (assessed by an as yet unvalidated family functioning measure). No significant difference was found between the groups in family functioning or children's self-concept. The two groups of chronically ill children did have significantly higher frequencies of behavior problems than had the healthy children. When there was statistical control for effects related to family functioning, however, this difference was not significant. Family functioning was found to be a better predictor of child adjustment than was the presence of illness. These results are consistent with recent research suggesting that children with cystic fibrosis adjust in basically healthy ways and that any deficits result more from mediating factors. In this study family functioning was found to be an important mediating factor in this process.

UI	MeSH Term	Description	Entries
D008297	Male		Males
D002648	Child	A person 6 to 12 years of age. An individual 2 to 5 years old is CHILD, PRESCHOOL.	Children
D002653	Child Behavior Disorders	Disturbances considered to be pathological based on age and stage appropriateness, e.g., conduct disturbances and anaclitic depression. This concept does not include psychoneuroses, psychoses, or personality disorders with fixed patterns.	Childhood Behavior Disorders,Behavior Disorder, Child,Behavior Disorder, Childhood,Child Behavior Disorder,Childhood Behavior Disorder,Disorder, Childhood Behavior
D003550	Cystic Fibrosis	An autosomal recessive genetic disease of the EXOCRINE GLANDS. It is caused by mutations in the gene encoding the CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR expressed in several organs including the LUNG, the PANCREAS, the BILIARY SYSTEM, and the SWEAT GLANDS. Cystic fibrosis is characterized by epithelial secretory dysfunction associated with ductal obstruction resulting in AIRWAY OBSTRUCTION; chronic RESPIRATORY INFECTIONS; PANCREATIC INSUFFICIENCY; maldigestion; salt depletion; and HEAT PROSTRATION.	Mucoviscidosis,Cystic Fibrosis of Pancreas,Fibrocystic Disease of Pancreas,Pancreatic Cystic Fibrosis,Pulmonary Cystic Fibrosis,Cystic Fibrosis, Pancreatic,Cystic Fibrosis, Pulmonary,Fibrosis, Cystic,Pancreas Fibrocystic Disease,Pancreas Fibrocystic Diseases
D005190	Family	A social group consisting of parents or parent substitutes and children.	Family Life Cycles,Family Members,Family Life Cycle,Family Research,Filiation,Kinship Networks,Relatives,Families,Family Member,Kinship Network,Life Cycle, Family,Life Cycles, Family,Network, Kinship,Networks, Kinship,Research, Family
D005260	Female		Females
D006801	Humans	Members of the species Homo sapiens.	Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D001249	Asthma	A form of bronchial disorder with three distinct components: airway hyper-responsiveness (RESPIRATORY HYPERSENSITIVITY), airway INFLAMMATION, and intermittent AIRWAY OBSTRUCTION. It is characterized by spasmodic contraction of airway smooth muscle, WHEEZING, and dyspnea (DYSPNEA, PAROXYSMAL).	Asthma, Bronchial,Bronchial Asthma,Asthmas
D012649	Self Concept	Persons' view of themselves.	Self Esteem,Self Perception,Self Confidence,Self-Perception,Concept, Self,Confidence, Self,Esteem, Self,Perception, Self,Perceptions, Self,Self Esteems,Self Perceptions,Self-Perceptions
D012917	Social Adjustment	Adaptation of the person to the social environment. Adjustment may take place by adapting the self to the environment or by changing the environment. (From Campbell, Psychiatric Dictionary, 1996).	Adjustment, Social,Adjustments, Social,Social Adjustments