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The function of 111In-labelled platelets has been assessed by collagen-induced aggregation of platelets in samples of whole blood. The blood samples were drawn after injection of autologous 111In-labelled platelets in 19 subjects undergoing platelet kinetic studies. It was thus possible to measure the aggregability of labelled and unmanipulated platelets simultaneously. 111In-labelled platelets aggregated to the same extent as unmanipulated platelets when tested from 10 min to 24 h after injection of the labelled platelets. The results confirm the assumption that minimal damage is inflicted on the platelets during the isolation and labelling procedures, and support the concept that platelets manipulated in vitro may recover in vivo within a few minutes after reinjection.
K G Schmidt, and
J W Rasmussen, and
H Arendrup
March 1980,
Clinical science (London, England : 1979),
K G Schmidt, and
J W Rasmussen, and
H Arendrup
May 1986,
Thrombosis research,
K G Schmidt, and
J W Rasmussen, and
H Arendrup
October 1988,
Nuclear medicine communications,
K G Schmidt, and
J W Rasmussen, and
H Arendrup
December 1968,
The Journal of clinical investigation,
K G Schmidt, and
J W Rasmussen, and
H Arendrup
October 1975,
Scandinavian journal of haematology,
K G Schmidt, and
J W Rasmussen, and
H Arendrup
July 1972,
Thrombosis et diathesis haemorrhagica,
K G Schmidt, and
J W Rasmussen, and
H Arendrup
January 2012,
Internal medicine (Tokyo, Japan),
K G Schmidt, and
J W Rasmussen, and
H Arendrup
January 1982,
The International journal of applied radiation and isotopes,
K G Schmidt, and
J W Rasmussen, and
H Arendrup
April 1971,
The American journal of physiology,
K G Schmidt, and
J W Rasmussen, and
H Arendrup
May 1970,
Journal of medicinal chemistry,
