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The effect of the administration of vitamin A drops on neutralizing the inhibitory role of cortisone in penetrating corneal wound healing was studied on 24 albino rabbits (48 eyes). The rate of healing of the wound was determined by the fluorescein strain technique and the tensile strength of the affected cornea was determined on the 11th day after the wound was made. It was observed that in the group of eyes in which only cortisone in any form was administered, not only was the rate of healing delayed (with statistical significance) but there was also a statistically significant lowering of the tensile strength of the wound. However, in the eyes in which vitamin A was also administered simultaneously with cortisone, the rate of healing of the wound was enhanced and there was also a statistically significant increase in the tensile strength of wound. Therefore in this study it was confirmed that by simultaneous use of vitamin A drops, the inhibitory role of cortisone is neutralized even in penetrating corneal wounds.
K S Mehra, and
I Mikuni, and
A Kumar
November 1951,
The British journal of ophthalmology,
K S Mehra, and
I Mikuni, and
A Kumar
March 1968,
Annals of surgery,
K S Mehra, and
I Mikuni, and
A Kumar
June 1965,
Nippon Ganka Gakkai zasshi,
K S Mehra, and
I Mikuni, and
A Kumar
February 1961,
American journal of surgery,
K S Mehra, and
I Mikuni, and
A Kumar
August 1954,
Bollettino d'oculistica,
K S Mehra, and
I Mikuni, and
A Kumar
January 1985,
Oftalmologicheskii zhurnal,
K S Mehra, and
I Mikuni, and
A Kumar
August 1969,
Annals of surgery,
K S Mehra, and
I Mikuni, and
A Kumar
October 1969,
Annals of surgery,
K S Mehra, and
I Mikuni, and
A Kumar
January 1955,
Vestnik oftalmologii,
K S Mehra, and
I Mikuni, and
A Kumar
November 2016,
Experimental and therapeutic medicine,
