Biomaterial Database

Behaviour-dependent changes of visually evoked potentials and their correlation to the respiration rate in freely moving rats. 1982

J Brankack, and F Klingberg

The variability of visually evoked potentials (VEP) during spontaneous changes of behavioural activity was investigated in freely moving rats with electrodes in the visual and frontal cortex, olfactory bulb and other brain structures. Averaged VEP were recorded and compared during periods of characteristic behaviour types like drowsiness, relaxed wakefulness, attentiveness, grooming and exploratory behaviour. These behavioural patterns, which are clearly distinguishable by observation, were characterized by a certain degree of visually evoked afterdischarges, recorded movements, EEG-patterns and mean respiration rate. The evaluation of early components of the VEP from single recorded samples and of the correspondent momentary respiration rate (respiration intervals) revealed strongly negative correlations. In general, the increasing behavioural activity is characterized by a decrease in the amplitudes of VEP-components, inversely correlated to the log of momentary respiration rate. During drowsiness and enhanced attentiveness, certain components are increased. During strong movements and distraction of attention (e.g. intensive scratching and licking) the VEP-components were decreased stronger. The negative complex around 62 ms increased during certain forms of behavioural activation and locomotion. The VEP-component N31, the respiration rate, and the quotient N31: N61 were found suitable parameters to characterize certain types of behaviour in comparison to relaxed wakefulness.

UI	MeSH Term	Description	Entries
D008297	Male		Males
D012119	Respiration	The act of breathing with the LUNGS, consisting of INHALATION, or the taking into the lungs of the ambient air, and of EXHALATION, or the expelling of the modified air which contains more CARBON DIOXIDE than the air taken in (Blakiston's Gould Medical Dictionary, 4th ed.). This does not include tissue respiration (	Breathing
D005074	Evoked Potentials, Visual	The electric response evoked in the cerebral cortex by visual stimulation or stimulation of the visual pathways.	Visual Evoked Response,Evoked Potential, Visual,Evoked Response, Visual,Evoked Responses, Visual,Potential, Visual Evoked,Potentials, Visual Evoked,Response, Visual Evoked,Responses, Visual Evoked,Visual Evoked Potential,Visual Evoked Potentials,Visual Evoked Responses
D005106	Exploratory Behavior	The tendency to explore or investigate a novel environment. It is considered a motivation not clearly distinguishable from curiosity.	Curiosity,Novelty-Seeking Behavior,Behavior, Exploratory,Behavior, Novelty-Seeking,Behaviors, Exploratory,Behaviors, Novelty-Seeking,Curiosities,Exploratory Behaviors,Novelty Seeking Behavior,Novelty-Seeking Behaviors
D006120	Grooming	An animal's cleaning and caring for the body surface. This includes preening, the cleaning and oiling of feathers with the bill or of hair with the tongue.	Preening,Groomings,Preenings
D000818	Animals	Unicellular or multicellular, heterotrophic organisms, that have sensation and the power of voluntary movement. Under the older five kingdom paradigm, Animalia was one of the kingdoms. Under the modern three domain model, Animalia represents one of the many groups in the domain EUKARYOTA.	Animal,Metazoa,Animalia
D001288	Attention	Focusing on certain aspects of current experience to the exclusion of others. It is the act of heeding or taking notice or concentrating.	Focus of Attention,Selective Attention,Social Attention,Attention Focus,Attention, Selective,Attention, Social,Selective Attentions
D001522	Behavior, Animal	The observable response an animal makes to any situation.	Autotomy Animal,Animal Behavior,Animal Behaviors
D012894	Sleep Stages	Periods of sleep manifested by changes in EEG activity and certain behavioral correlates; they formerly included Stage 1: sleep onset, drowsy sleep; Stage 2: light sleep; Stages 3 and 4: delta sleep, light sleep, deep sleep, telencephalic sleep. In 2007, sleep stages were redefined by The American Academy of Sleep Medicine (AASM) as: N1-N2 (sleep onset - light sleep), N3 (SLOW-WAVE SLEEP), and REM SLEEP.	N1-Sleep,N2-Sleep,NREM Stage 1,NREM Stage 2,N1 Sleep,N2 Sleep,Sleep Stage,Stage, Sleep,Stages, Sleep
D051381	Rats	The common name for the genus Rattus.	Rattus,Rats, Laboratory,Rats, Norway,Rattus norvegicus,Laboratory Rat,Laboratory Rats,Norway Rat,Norway Rats,Rat,Rat, Laboratory,Rat, Norway,norvegicus, Rattus