Biomaterial Database

Electronystagmographic and audiologic findings in patients with Meniere's disease. 1982

R A Dobie, and J M Snyder, and J A Donaldson

Electronystagmographic (ENG) and audiologic findings were reviewed for 206 patients treated for Meniere's disease (MD) at the University of Washington Hospital over a 10-year period (1971-80). The most frequently seen ENG findings were unilateral caloric weakness (UW) in 49%, directional preponderance (DP) in 36%, and spontaneous and/or positional nystagmus (SN, PN) in 32%. ENG was normal in 25%. Bilateral caloric weakness (BW) occurred in 36% of patients with bilateral hearing loss. UW was reliably correlated with the side of audiometric involvement; after exclusion of bilateral cases, only 3% of patients showed UW contralateral to the ear with hearing los. Neither DP nor direction of SN or PN correlated at all with side of hearing loss. There was no significant correlation of severity of hearing loss (by pure-tone thresholds or speech discrimination score) with ENG abnormality (UW or DP). Glycerol-positive patients had significantly poorer hearing than glycerol-negative patients, but ENG findings were similar in the two groups.

UI	MeSH Term	Description	Entries
D008297	Male		Males
D008575	Meniere Disease	A disease of the inner ear (LABYRINTH) that is characterized by fluctuating SENSORINEURAL HEARING LOSS; TINNITUS; episodic VERTIGO; and aural fullness. It is the most common form of endolymphatic hydrops.	Meniere's Disease,Meniere's Syndrome,Vertigo, Aural,Auditory Vertigo,Aural Vertigo,Ménière Disease,Ménière's Disease,Ménière's Vertigo,Otogenic Vertigo,Auditory Vertigos,Disease, Meniere,Disease, Meniere's,Disease, Ménière,Disease, Ménière's,Diseases, Ménière,Diseases, Ménière's,Meniere Syndrome,Menieres Disease,Menieres Syndrome,Ménière Diseases,Ménière Vertigo,Ménière's Diseases,Ménière's Vertigos,Ménières Disease,Ménières Vertigo,Otogenic Vertigos,Syndrome, Meniere's,Vertigo, Auditory,Vertigo, Ménière's,Vertigo, Otogenic,Vertigos, Auditory,Vertigos, Ménière's,Vertigos, Otogenic
D008875	Middle Aged	An adult aged 45 - 64 years.	Middle Age
D002150	Caloric Tests	Elicitation of a rotatory nystagmus by stimulating the semicircular canals with water or air which is above or below body temperature. In warm caloric stimulation a rotatory nystagmus is developed toward the side of the stimulated ear; in cold, away from the stimulated side. Absence of nystagmus indicates the labyrinth is not functioning.	Barany Test,Barany's Test,Baranys Test,Caloric Test,Test, Barany,Test, Barany's,Test, Caloric,Tests, Caloric
D004584	Electronystagmography	Recording of nystagmus based on changes in the electrical field surrounding the eye produced by the difference in potential between the cornea and the retina.	Electronystagmographies
D005260	Female		Females
D005990	Glycerol	A trihydroxy sugar alcohol that is an intermediate in carbohydrate and lipid metabolism. It is used as a solvent, emollient, pharmaceutical agent, or sweetening agent.	1,2,3-Propanetriol,Glycerin,1,2,3-Trihydroxypropane,Glycerine
D006801	Humans	Members of the species Homo sapiens.	Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D001299	Audiometry	The testing of the acuity of the sense of hearing to determine the thresholds of the lowest intensity levels at which an individual can hear a set of tones. The frequencies between 125 and 8000 Hz are used to test air conduction thresholds and the frequencies between 250 and 4000 Hz are used to test bone conduction thresholds.	Audiometries
D001309	Auditory Threshold	The audibility limit of discriminating sound intensity and pitch.	Auditory Thresholds,Threshold, Auditory,Thresholds, Auditory