The Lukes and Collins classification of non-Hodgkin's lymphomas. I. A histological reappraisal of 301 cases. 1982

M Alavaikko, and R Aine

Cytomorphological categories of the Lukes and Collins classification could be recognized in 92% out of a retrospective series of 301 non-Hodgkin's lymphomas. The follicular center cell (FCC) group constituted the majority (54%). Certain differences between the cytological subgroups were observed as regards age and sex and the growth pattern. Follicular features in the growth pattern were found in 16% of the cases. The large cleaved FCC type behaved differently from the other FCC types in many respects. The occurrence of cleaved FCC lymphomas appeared to be exceptional in childhood. There were no small lymphocytic and plasmacytoid lymphocytic lymphomas in children or young adults, and large non-cleaved FCC lymphomas and immunoblastic sarcomas were rare in these. In the small non-cleaved FCC group both the Burkitt type and the non-Burkitt type exhibited a bimodal age distribution with a peak under 10 years of age and another at age 60-70 years. Five convoluted lymphocyte lymphomas, between 2 and 29 years of age, were found in this series. The heterogeneous group of unclassified lymphomas included as a special case one lymphoma with deeply multilobated nuclei.

UI MeSH Term Description Entries
D008223 Lymphoma A general term for various neoplastic diseases of the lymphoid tissue. Germinoblastoma,Lymphoma, Malignant,Reticulolymphosarcoma,Sarcoma, Germinoblastic,Germinoblastic Sarcoma,Germinoblastic Sarcomas,Germinoblastomas,Lymphomas,Lymphomas, Malignant,Malignant Lymphoma,Malignant Lymphomas,Reticulolymphosarcomas,Sarcomas, Germinoblastic
D008297 Male Males
D008875 Middle Aged An adult aged 45 - 64 years. Middle Age
D002648 Child A person 6 to 12 years of age. An individual 2 to 5 years old is CHILD, PRESCHOOL. Children
D002675 Child, Preschool A child between the ages of 2 and 5. Children, Preschool,Preschool Child,Preschool Children
D005260 Female Females
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000293 Adolescent A person 13 to 18 years of age. Adolescence,Youth,Adolescents,Adolescents, Female,Adolescents, Male,Teenagers,Teens,Adolescent, Female,Adolescent, Male,Female Adolescent,Female Adolescents,Male Adolescent,Male Adolescents,Teen,Teenager,Youths
D000328 Adult A person having attained full growth or maturity. Adults are of 19 through 44 years of age. For a person between 19 and 24 years of age, YOUNG ADULT is available. Adults
D000367 Age Factors Age as a constituent element or influence contributing to the production of a result. It may be applicable to the cause or the effect of a circumstance. It is used with human or animal concepts but should be differentiated from AGING, a physiological process, and TIME FACTORS which refers only to the passage of time. Age Reporting,Age Factor,Factor, Age,Factors, Age

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