[Ultrasonic hemolysis of normal and pathological erythrocytes]. 1982

F I Braginskaia, and G G Sultanova, and V B Akopian, and D B Korman, and K E Krugliakova

The kinetic method of the investigation of erythrocyte haemolysis normal and at different tumour pathologies by ultrasound was developed. The quantitative parameters of the mechanical resistance of erythrocytes were studied (time and velocity of haemolysis, time of half-destruction, the distribution of erythrocytes by their haemolytic resistance). The studied parameters differ between the normal state and the tumour in organism. The analysis of the differential distribution of erythrocytes by their resistance to ultrasonic haemolysis revealed the occurrence in the patient's blood of erythrocytes with increased resistance ("young" erythrocytes). The mechanical resistance of the erythrocytes at pathology was shown to increase as compared with the normal state. The differences in the effective constants of ultrasonic haemolysis velocity were estimated for the normal state and for different tumours. They are caused by the changes in visco-elastic properties of red blood cells.

UI MeSH Term Description Entries
D007700 Kinetics The rate dynamics in chemical or physical systems.
D009369 Neoplasms New abnormal growth of tissue. Malignant neoplasms show a greater degree of anaplasia and have the properties of invasion and metastasis, compared to benign neoplasms. Benign Neoplasm,Cancer,Malignant Neoplasm,Tumor,Tumors,Benign Neoplasms,Malignancy,Malignant Neoplasms,Neoplasia,Neoplasm,Neoplasms, Benign,Cancers,Malignancies,Neoplasias,Neoplasm, Benign,Neoplasm, Malignant,Neoplasms, Malignant
D004905 Erythrocyte Aging The senescence of RED BLOOD CELLS. Lacking the organelles that make protein synthesis possible, the mature erythrocyte is incapable of self-repair, reproduction, and carrying out certain functions performed by other cells. This limits the average life span of an erythrocyte to 120 days. Erythrocyte Survival,Aging, Erythrocyte,Survival, Erythrocyte
D004912 Erythrocytes Red blood cells. Mature erythrocytes are non-nucleated, biconcave disks containing HEMOGLOBIN whose function is to transport OXYGEN. Blood Cells, Red,Blood Corpuscles, Red,Red Blood Cells,Red Blood Corpuscles,Blood Cell, Red,Blood Corpuscle, Red,Erythrocyte,Red Blood Cell,Red Blood Corpuscle
D006461 Hemolysis The destruction of ERYTHROCYTES by many different causal agents such as antibodies, bacteria, chemicals, temperature, and changes in tonicity. Haemolysis,Extravascular Hemolysis,Intravascular Hemolysis,Extravascular Hemolyses,Haemolyses,Hemolyses, Extravascular,Hemolyses, Intravascular,Hemolysis, Extravascular,Hemolysis, Intravascular,Intravascular Hemolyses
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D014465 Ultrasonics A subfield of acoustics dealing in the radio frequency range higher than acoustic SOUND waves (approximately above 20 kilohertz). Ultrasonic radiation is used therapeutically (DIATHERMY and ULTRASONIC THERAPY) to generate HEAT and to selectively destroy tissues. It is also used in diagnostics, for example, ULTRASONOGRAPHY; ECHOENCEPHALOGRAPHY; and ECHOCARDIOGRAPHY, to visually display echoes received from irradiated tissues. Ultrasonic

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