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Experiments on normal dogs were made to study the effect of hemosorption on some of the characteristics marking down the hemostatic system: the content of platelets and fibrinogen, the times of plasma recalcification and euglobulin lysis, the prothrombin time, the ethanol and protamine sulfate tests, and fibrinase activity. Hemosorption produces no abrupt shifts on the part of the blood coagulation system. Additional administration of heparin does not prevent "caking" of the sorbent. The reduction in the number of circulating platelets induced by hemosorption is then replaced by pronounced thrombocytosis.
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